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MetabolomicsA metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance
Tissues are exposed to diverse inflammatory challenges that shape future inflammatory responses. While cellular metabolism regulates immune function, how metabolism programs and stabilizes immune states within tissues and tunes susceptibility to inflammation is poorly understood. Here, we describe a...
2024-10-25 | MTBLS10416 | MetaboLights
MetabolomicsA Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
GenomicsRNA-seq and RRBS of developing zebrafish larval brain and WGBS of 4 week old WT and dnmt3aa/dnmt3ab CRISPR/CAS9 KO brain
DNA methylation predominantly occurs at CG dinucleotides in vertebrate genomes, however, non-CG methylation (mCH) is also detectable in vertebrate tissues, most notably in the nervous system. In mammalian brains, it is well established that: i) mCH is targeted to CAC trinucleotides by DNMT3A, ii) en...
ORGANISM(S): Danio rerio 
2020-12-18 | E-MTAB-9924 | biostudies-arrayexpress
UnknownIxazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance.
Not available
S-EPMC6755968 | biostudies-literature
UnknownInternal state configures olfactory behavior and early sensory processing in Drosophila larvae.
Not available
S-EPMC7775770 | biostudies-literature
UnknownStructured Odorant Response Patterns across a Complete Olfactory Receptor Neuron Population.
Not available
S-EPMC6756926 | biostudies-literature
UnknownSequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains.
Not available
S-EPMC3429126 | biostudies-literature
MetabolomicsJasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
Foliar stomatal movements are critical for regulating plant water loss and gas exchange. Elevated carbon dioxide (CO2) levels are known to induce stomatal closure. However, the current knowledge on CO2 signal transduction in stomatal guard cells is limited. Here we report metabolomic responses of Br...
2017-04-25 | MTBLS312 | MetaboLights
UnknownPan-neuronal imaging in roaming Caenorhabditis elegans.
Not available
S-EPMC4776525 | biostudies-literature
UnknownPhenotype-Based Threat Assessment.
Not available
S-EPMC9168455 | biostudies-literature
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