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TranscriptomicsTranscriptomic signature induced in bone marrow Mesenchymal Stromal Cells (MSC) after interaction with malignant multiple myeloma cells: implications in myeloma progression.
Mesenchymal stromal cells (MSCs) derived from the BM of healthy donors (dMSCs) and myeloma patients (pMSCs) were co-cultured with the model myeloma cell line - MM.1S -, and the gene expression profile of MSCs induced by this interaction was analyzed using high density oligonucleotide microarrays. De...
ORGANISM(S): Homo sapiens 
2014-11-23 | E-GEOD-46053 | biostudies-arrayexpress
TranscriptomicsBisphosphonate related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in MM
We have explored the potential role of genetics in the development of osteonecrosis of the jaw (ONJ) in multiple myeloma (MM) patients under bisphosphonate therapy. A genome wide association study was performed using 500.568 single nucleotide polymorphisms (SNPs) in two series of homogeneously treat...
ORGANISM(S): Homo sapiens 
2008-09-25 | E-GEOD-11948 | biostudies-arrayexpress
UnknownHealth-Related Quality-of-Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.
Not available
S-EPMC5791840 | biostudies-literature
UnknownDepth of Response in Multiple Myeloma: A Pooled Analysis of Three PETHEMA/GEM Clinical Trials.
Not available
S-EPMC5568033 | biostudies-literature
UnknownThe transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients.
Not available
S-EPMC9729799 | biostudies-literature
UnknownGenomic analysis of high-risk smoldering multiple myeloma.
Not available
S-EPMC3436247 | biostudies-literature
UnknownBendamustine, bortezomib and prednisone for the treatment of patients with newly diagnosed multiple myeloma: results of a prospective phase 2 Spanish/PETHEMA trial.
Not available
S-EPMC5004426 | biostudies-literature
UnknownPatterns of relapse and outcome of elderly multiple myeloma patients treated as front-line therapy with novel agents combinations.
Not available
S-EPMC4588395 | biostudies-literature
TranscriptomicsThe cellular origin and malignant transformation of Waldenström's Macroglobulinemia [gene expression]
Although information on the molecular pathogenesis of Waldenström’s Macroglobulinemia (WM) has greatly improved in recent years, the exact cellular origin and the mechanisms behind WM transformation from IgM MGUS remain undetermined. Here, we undertook an integrative phenotypic, molecular and genomi...
ORGANISM(S): Homo sapiens 
2015-05-05 | E-GEOD-61597 | biostudies-arrayexpress
UnknownTargeting CD38 with isatuximab and a novel CD38/CD3×CD28 trispecific T-cell engager in older patients with acute myeloid leukemia.
Not available
S-EPMC11321322 | biostudies-literature
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