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A housing-based socioeconomic index (HOUSES) was previously developed to overcome an absence of socioeconomic status (SES) measures in common databases. HOUSES is associated with child health outcomes in Olmsted County, Minnesota, USA, but generalisability to other geographic area...
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
This paper describes the systematic study of metal-organic framework (MOF) catalysts for the reaction of propylene oxide (PO) with carbon dioxide (CO2) to generate propylene carbonate (PC). These studies began with the evaluation of MIL-101(Cr) as catalyst in a flow reactor. Under the dev...
Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00551 PASS00551]]. File: SBEP_STM_subcell-53c_14Jan11_Doc_10-09-53.mzml. Published as part of . From the Abstract: {{i}} Towards developing a systems-level pathobiological understanding of Salmonella enterica, we performed a subcellular...
ORGANISM(S): Salmonella_phage_c341_uid39795,salmonella_phage_e1_uid29079,salmonella_phage_epsilon34_uid33779,salmonella_phage_fels_1_uid29267,salmonella_phage_phisg_jl2_uid30063,salmonella_phage_se1_uid33483,salmonella_phage_setp3_uid19157,salmonella_phage_st64b_uid14228, Salmonella_enterica_serovar_typhimurium_14028s 
Many viral pathogens target innate sensing cascades and/or cellular transcription factors to suppress antiviral immune responses. Here, we show that the accessory viral protein U (Vpu) of HIV-1 exerts broad immunosuppressive effects by inhibiting activation of the transcription factor NF-κB. Global ...
Nitric oxide (NO) is generated from arginine and oxygen via NO synthase (NOS). Staphylococcus aureus NOS (saNOS) has previously been shown to affect virulence and resistance to exogenous oxidative stress, yet the exact mechanism is unknown. Herein, a previously undescribed role of saNOS in S. aureus...
Basal autophagy is a crucial mechanism in cellular homeostasis, underlying both normal cellular recycling and the clearance of damaged or misfolded proteins, organelles and aggregates. We showed here that enhanced levels of autophagy induced by either autophagic gene overexpression or voluntary exer...
Investigating the impacts on MS data quantitation reproducibility when loading differential amounts of peptides, ranging from 20 to 400 ug, across channels of TMT 11 multiplexes. PTRC_Exp9 files represent global proteome and phosphoproteome data generated from PBMCs isolated from AML patients, acqui...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-05 | MSV000086417 | MassIVE
"Shock and kill" strategies focus on purging the latent HIV-1 reservoir by treating infected individuals with therapeutics that activate the latent virus and subsequently eliminating infected cells. We have previously reported that induction of non-canonical nuclear factor κB (NF-κB) signaling throu...
Kinase signaling fuels growth of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Yet its role in leukemia initiation is unclear and has not been shown in primary human hematopoietic cells. We previously described activating mutations in interleukin-7 receptor alpha (IL7RA) in poor-prognosis...
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