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TranscriptomicsGenome wide mapping of H3K27me3 in differentiated mouse podocytes
We explored H3K27me3 binding sites in the genome of differentiated, conditionally immortalized mouse podocytes. Cells were allowed to differentiate for 14 days, following thermoshifting, before treatment with either vehicle (DMSO) or the S-adenosylhomocysteine hydrolase inhibitor 3-deazaneplanocin ...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-69610 | biostudies-arrayexpress
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
UnknownThe 2018 Lake Louise Acute Mountain Sickness Score.
Not available
S-EPMC6191821 | biostudies-literature
UnknownHistone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.
Not available
S-EPMC6205459 | biostudies-literature
TranscriptomicsGenome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes
Analysis of DZNep-induced gene expression changes in cultured podocytes. The hypothesis tested in the present study was that DZnep ultimately augments Txnip expression, increasing oxidative stress in podocytes. These results provide important information on the response of podocytes to histone methy...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-60038 | biostudies-arrayexpress
ProteomicsTarget deconvolution of SW016789 in human and mouse Beta cells
The target of SW016789 is unknown (PMCID: PMC9225822). This compound was identified in a high-throughput screen for insulin secretion modulators and was subsequently discovered to cause hypersecretory stress in beta cells. A photoaffinity probe was designed, Z629, based upon the structure of SW01678...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2024-03-13 | MSV000094310 | MassIVE
UnknownThe Importance of Frailty in the Assessment of Influenza Vaccine Effectiveness Against Influenza-Related Hospitalization in Elderly People.
Not available
S-EPMC5853583 | biostudies-literature
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
Not available
S-EPMC12519944 | biostudies-literature
UnknownInfluenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada.
Not available
S-EPMC5747268 | biostudies-literature
UnknownIdentification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Not available
S-EPMC4962376 | biostudies-literature
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