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Gel based approach : Concanavalin A bound fiber glycoproteins were resolved through SDS PAGE followed by identification of trypsinised gel pieces through Nano-LC MALDI TOF/TOF. Solution based approach: Concanavalin A bound fiber glycoproteins were solution phase digested and fractionated through SC...
ORGANISM(S): Gossypium 
2014-03-18 | PXD000178 | Pride

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1627 | MetaboLights

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS2885 | MetaboLights
Bacterial pathogens exploit secreted aminopeptidases to modulate host cellular functions. Mycobacterium tuberculosis (Mtb) secretes PepN, a M1 aminopeptidase with N-terminal peptidase and C-terminal ERAP1_C-like domains. In addition to being conserved across Mtb complex, PepNMtb is also homologous (...
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium smegmatis 
2019-07-29 | PXD009164 | Pride
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