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TranscriptomicsDmrt1 (doublesex and mab-3 related transcription factor 1) knockout expression analyses in E13.5 testes in S6 background
Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular development in vertebrates. In mice of the 129Sv strain, loss of Dmrt1 causes a high incidence of teratomas. Mutant 129Sv germ cells undergo apparently...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-18396 | biostudies-arrayexpress
TranscriptomicsAnalyses of mIRNA transcript level following exposure to triptolide
Analyses of mirna transcript levels following exposure to the drug triptolide in vitro and prodrug minnelide in xenograft pancreatic tumor mouse models. Response of pancreatic adenocarcinoma cell lines to minelide in vitro and exposure to its prodrug triptolide in SCID mouse tumors derived from the ...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-46188 | biostudies-arrayexpress
TranscriptomicsDmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of P28 testes
Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular development in vertebrates. This study examines the result of conditional removal of Dmrt1 from Sertoli cells in P28 testis tissue. Testes from P28 Dmr...
ORGANISM(S): Mus musculus 
2011-07-28 | E-GEOD-27261 | biostudies-arrayexpress
TranscriptomicsGene expression following myocardial infarction with and without stem cell transplantation
Background: Bone marrow-derived multipotent progenitor cell (MPC) transplantation leads to short term functional and bioenergetic improvement in a porcine model of postinfarction Left Ventricular (LV) remodeling despite a low engraftment rate. However, the long term outcome after MPC transplantation...
ORGANISM(S): Sus scrofa 
2010-04-12 | E-GEOD-14643 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in response to bortezomib treatment [human cell lines].
Genome-wide analysis of gene expression in response to bortezomib treatment (33 nM) in cell lines before and after selection for resistance. Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of neoplastic plasma cells in the bone marrow. While the first-to-market p...
ORGANISM(S): Homo sapiens 
2013-07-02 | E-GEOD-41929 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in response to bortezomib treatment [mouse cell lines II]
Genome-wide analysis of gene expression in response to bortezomib treatment(33 nM) in cell lines before and after selection for resistance. Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of neoplastic plasma cells in the bone marrow. While the first-to-market pr...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-41928 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in response to bortezomib treatment [mouse cell lines I]
Genome-wide analysis of gene expression in response to bortezomib treatment (33 nM) in cell lines before and after selection for resistance. Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of neoplastic plasma cells in the bone marrow. While the first-to-market p...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-41927 | biostudies-arrayexpress
TranscriptomicsConditional Dmrt1 knockout gene expression (phase 6)
Genome wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis. Gene expression differences found in conditionally targeted P9 testes were compared to those of controls
ORGANISM(S): Mus musculus 
2010-06-30 | E-GEOD-22500 | biostudies-arrayexpress
TranscriptomicsConditional Dmrt1 knockout gene expression (phase 7)
Genome wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis. Gene expression differences found in conditionally targeted P9 testes were compared to those of controls
ORGANISM(S): Mus musculus 
2010-06-30 | E-GEOD-22507 | biostudies-arrayexpress
TranscriptomicsConditional Dmrt1 knockout gene expression (phase 8)
Genome wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis. Gene expression differences found in conditionally targeted P9 testes were compared to those of controls
ORGANISM(S): Mus musculus 
2010-06-30 | E-GEOD-22508 | biostudies-arrayexpress
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