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ProteomicsRefDIC Protein profiling of mouse immune cells
Not available
ORGANISM(S): Mus musculus (Mouse) 
2011-04-15 | PRD000029 | Pride
UnknownA gap balancing technique for adjusting the component gap in total knee arthroplasty using a navigation system.
Not available
S-EPMC7203512 | biostudies-literature
TranscriptomicsIdentification of Myt1 as a subunit of the neural cell type-specific LSD1 complex
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. Recently, dynamic epigenomic regulation, including chromatin remodeling and histone modifications by tra...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-49685 | biostudies-arrayexpress
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
TranscriptomicsArray CGH data of A. oryzae strains bearing targeted tandem chromosomal duplications
We here describe the first successful construction of a targeted tandem duplication of a large chromosomal segment in Aspergillus oryzae. The targeted tandem chromosomal duplication was achieved by using strains that had 5M-bM-^@M-^YM-NM-^TpyrG upstream of the region targeted for tandem chromosomal ...
ORGANISM(S): Aspergillus oryzae RIB40 
2014-06-30 | E-GEOD-57246 | biostudies-arrayexpress
TranscriptomicsGene repression with H3K27me3 modification in human small cell lung cancer
Small cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis due to early dissemination and rapid growth. We here analyze gene expression profile of 23 clinical SCLC samples. EZH2 was found to be highly expressed in SCLC samples compared to 42 normal tissues including the normal lun...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-43346 | biostudies-arrayexpress
Proteomicsβ-Nicotinamide mononucleotide restores mitochondrial function and muscle strength in septic male mice
Sepsis remains a leading cause of mortality and long-term disability, with survivors frequently developing intensive care unit–acquired weakness (ICU-AW) as part of post-intensive care syndrome. To identify a nutritional therapy for ICU-AW, we investigated the mechanisms underlying sepsis- induced s...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-01 | PXD072078 | Pride
Skeletal muscle weakness Sepsis Mitochondria icu-acquired weakness (icu-aw) Β-nmn 
UnknownCohort-Specific Optimization of Models Predicting Preclinical Alzheimer's Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer's Disease Clinical Studies.
Not available
S-EPMC12280815 | biostudies-literature
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