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ProteomicsUbiquitination analysis of OTUD5
TMT quantification of UBR5 knockdown HT1080 cells. Label-free quantification of OTUD5-interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-02-20 | PXD054556 | Pride
Human ht1080 cells Hek293t cells Ubiquitin 
TranscriptomicsExpression analysis of Arabidopsis mpk11 mutant treated with flg22
Arabidopsis MPK11 is activated and plays a role in the flg22 sensing. Mitogen-activated protein kinases (MAPKs) mediate cellular signal transduction during stress responses, as well as diverse growth and developmental steps in eukaryotes. Pathogen infection or treatment with conserved pathogen-assoc...
ORGANISM(S): Arabidopsis thaliana 
2012-05-02 | E-GEOD-33648 | biostudies-arrayexpress
TranscriptomicsModeling regulatory relationships in Arabidopsis immune signaling network.
Expression profiles of 22 reference Arabidopsis immunity mutants were collected using the Arabidopsis Pathoarray 464_001 (GPL3638) in order to build a network model predicting the Arabidopsis immune signaling network. Biological signaling processes may be mediated by complex networks in which netwo...
ORGANISM(S): Arabidopsis thaliana 
2010-07-22 | E-GEOD-19663 | biostudies-arrayexpress
TranscriptomicsTrastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
Objective: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC ...
ORGANISM(S): Homo sapiens 
2012-06-02 | E-GEOD-38415 | biostudies-arrayexpress
TranscriptomicsDownregulation of the Wnt antagonist Dkk2 links loss of Sept4 and myofibroblastic transformation of hepatic stellate cells
Background/Aims: Sept4, a subunit of the septin cytoskeleton specifically expressed in quiescent hepatic stellate cells (HSCs), is downregulated through transdifferentiation to fibrogenic and contractile myofibroblastic cells. Since Sept4?/? mice are prone to liver fibrosis, we examined the unknown ...
ORGANISM(S): Mus musculus 
2012-06-02 | E-GEOD-24588 | biostudies-arrayexpress
TranscriptomicsMicroRNA Profile Predicts Recurrence of Hepatocellular Carcinoma in Milan Criteria Cases with Mild Liver Cirrhosis.
In this study, we utilized microRNA expression profiling to assess risk of HCC recurrence after liver resection. We examined microRNA expression profiling in paired tumor and non-tumor liver tissues of 73 HCC patients with mild cirrhosis (Child-Pugh A/B) who satisfy Milan Criteria. We constructed pr...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-21362 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of esophageal squamous cell carcinoma cell lines
Profiles of esophageal squamous cell carcinoma and normal esophageal normal epithelium normal cell line. Analysis provides validation of novel microRNA targets prediction algorithms. esophageal squamous cell carcinoma:14, normal epithelium cell:2
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-23964 | biostudies-arrayexpress
TranscriptomicsArabidopsis CBP60g Contributes to MAMP-Induced SA Accumulation and Is Involved in Disease Resistance
Salicylic acid (SA)-induced defense responses are important factors during effector triggered immunity and microbe-associated molecular pattern (MAMP)-induced immunity in plants. This article presents evidence that a member of the Arabidopsis CBP60 gene family, CBP60g, contributes to MAMP-triggered ...
ORGANISM(S): Arabidopsis thaliana 
2010-05-07 | E-GEOD-14237 | biostudies-arrayexpress
TranscriptomicsThe Genetic Network Controlling the Arabidopsis Transcriptional Response to Pseudomonas syringae pv. maculicola
Expression profiling of wild-type plants and mutants with defects in key components of the defense signaling network was used to model the Arabidopsis network 24 hours after infection by Pseudomonas syringae pv. maculicola strain Psm ES4326. Results using the Affymetrix ATH1 array revealed that expr...
ORGANISM(S): Arabidopsis thaliana 
2008-07-18 | E-GEOD-11009 | biostudies-arrayexpress
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