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TranscriptomicsGene expression analysis of diabetic kidney cortices obtained from ICAM-1 deficient mice and wild type mice.
In the present study, we aimed to determine the genes involved in inflammatory process of diabetic nephropathy. ICAM-1+/+ and ICAM-1-/- mice aged 8 weeks were divided into four groups: 1) nondiabetic ICAM-1+/+ mice (ND-WT), 2) nondiabetic ICAM-1-/- mice (ND-KO), 3) streptozotocin (STZ)-induced diab...
ORGANISM(S): Mus musculus 
2014-10-08 | E-GEOD-21390 | biostudies-arrayexpress
ProteomicsProteomics of human tau-transgenic mice reveals protein modules associated with tau pathologies
Abnormally accumulated tau protein aggregates are one of the hallmarks of dementia, including Alzheimer’s disease (AD), and are believed to play a critical role in neurodegeneration. In order to investigate proteomic alteration driven by tau aggregates, we implemented quantitative proteomics to anal...
ORGANISM(S): Mus Musculus (mouse) 
2022-07-05 | PXD031129 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse liver
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the liver, we compared the whole cell proteome of livers harvested from GCN1 CKO mice with that of wild-type mice.
ORGANISM(S): Mus Musculus (mouse) 
2023-04-01 | PXD030514 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse ileum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of ileum harvested from GCN1 CKO mice with that of wild-type m...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030518 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse duodenum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of duodenum harvested from GCN1 CKO mice with that of wild-typ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030517 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse inguinal white adipose tissue (iWAT)
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the inguinal white adipose tissue (iWAT), we compared the whole cell proteome of eWAT harvested from GCN1 CKO mice with that ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030516 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse jejunum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of jejunum harvested from GCN1 CKO mice with that of wild-type...
ORGANISM(S): Mus Musculus (mouse) 
2022-08-29 | PXD030519 | JPOST Repository
ProteomicsCross-linking MS analysis of HIV-2 Vpx-PHD3 protein interaction
This dataset presents chemical crosslinking mass spectrometry (CL-MS) analysis of protein-protein interactions between HIV-2 Vpx and PHD3. The experimental data includes MS spectra obtained from protein complexes comprising recombinant Vpx and PHD3 crosslinked using DSBU under physiological conditio...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059241 | JPOST Repository
ProteomicsPHD3-mediated HIV-2 Vpx peptide hydroxylation
This dataset contains comparative mass spectrometry analysis investigating proline hydroxylation of synthetic HIV-2 Vpx peptides under two conditions: with and without PHD3 enzyme treatment. The analysis was performed using a high-resolution mass spectrometer coupled to a nano-LC system. The dataset...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059242 | JPOST Repository
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