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TranscriptomicsTranscription profiling of rat embryo ductus arteriosis after maternal vitamin A administration
The effects of retinoic acid/vitamin A signal on the transcriptional profile of the ductus arteriosus during development were examined. Experiment Overall Design: Total RNA samples were isolated from pooled tissues obtained from Wister rat embryos on embryonic day 19 and 21, and from neonates on th...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3420 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat aorta and ductus arteriosus
The transcriptional profiles of the aorta and the ductus arteriosus during development were compared. Experiment Overall Design: Total RNA samples were isolated from pooled tissues obtained from Wister rat embryos on embryonic day 19 and 21, and from neonates on the day of birth (n>=120). The RNA w...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3422 | biostudies-arrayexpress
TranscriptomicsISR target genes revealed by comprehensive microarray network study using Perk -/-, Atf4 -/-, eIF2a S51A mutant, Fv2E-PERK
To identify the target genes of integrated stress reponse (ISR), we have employed whole genome microarray expression in MEF cells. ISR gene setimation under ER stress condition using Perk -/-, Atf4 -/-, eIF2a S51A mutant, Fv2E-PERK MEF cells
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-49598 | biostudies-arrayexpress
TranscriptomicsISR target genes in WAT and BAT of mAP::Fv2E-PERK
To identify the target genes of integrated stress reponse (ISR) in WAT and BAT, we have employed whole genome microarray expression in WAT and BAT specific Fv2E-PERK transgenic mice. The mAP::Fv2E-PERK transgenic mice were injected by AP20187 or mock.
ORGANISM(S): Mus musculus 
2015-08-05 | E-GEOD-49645 | biostudies-arrayexpress
TranscriptomicsDevelopment of miRNA expression signatures of MEFs deficient in a ER stress mediator ATF6a for tunicamycin treatment
To further development of our miRNA expression approach to ER stress, we have employed miRNA microarray expression profiling as a discovery platform to identify ER stress-responsible ones. Mouse embryonic fibroblasts (MEFs) deficient in a ER stress mediator ATF6a were treated with tunicamycin for ...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35176 | biostudies-arrayexpress
TranscriptomicsDevelopment of miRNA expression signatures of MEFs deficient in a ER stress mediator XBP1 for tunicamycin treatment
To further development of our miRNA expression approach to ER stress, we have employed miRNA microarray expression profiling as a discovery platform to identify ER stress-responsible ones. Mouse embryonic fibroblasts (MEFs) deficient in a ER stress mediator XBP1 were treated with tunicamycin for 1...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35174 | biostudies-arrayexpress
TranscriptomicsDevelopment of miRNA expression signatures of MEFs deficient in a ER stress mediator ATF4 for tunicamycin treatment
To further development of our miRNA expression approach to ER stress, we have employed miRNA microarray expression profiling as a discovery platform to identify ER stress-responsible ones. Mouse embryonic fibroblasts (MEFs) deficient in a ER stress mediator ATF4 were treated with tunicamycin for 1...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35175 | biostudies-arrayexpress
TranscriptomicsDevelopment of miRNA expression signatures of MEFs deficient in a ER stress mediator ATF6b for tunicamycin treatment
To further development of our miRNA expression approach to ER stress, we have employed miRNA microarray expression profiling as a discovery platform to identify ER stress-responsible ones. Mouse embryonic fibroblasts (MEFs) deficient in a ER stress mediator ATF6b were treated with tunicamycin for ...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35177 | biostudies-arrayexpress
TranscriptomicsDevelopment of mRNA and lincRNA expression signatures of MEFs deficient in ER stress mediators for tunicamycin treatment
To further development of our mRNA or lincRNA expression approach to ER stress, we have employed whole genome microarray expression profiling as a discovery platform to identify ER stress-responsible genes. Mouse embryonic fibroblasts (MEFs) deficient in each ER stress mediator (XBP1, ATF4, ATF6a ...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35173 | biostudies-arrayexpress
TranscriptomicsGene expression profile of ATF6a and ATF6b knockout mice with dextran sulfate sodium (DSS)-induced colitis
To understand the role of ATF6a and ATF6b in non-canonical endoplasmic reticulum stress response pathway, we have employed whole genome microarray expression profiling to identify the genes regulated by ATF6s. WIild type or, ER stress mediators,ATF6a or ATF6b-knockout mice were treated with 3% DSS ...
ORGANISM(S): Mus musculus 
2015-02-08 | E-GEOD-35651 | biostudies-arrayexpress
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