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GenomicsGenome-wide analysis of intracellular notch1(ICN1) targets in gamma delta T cells (gd T cells).
We performed chromatin immunoprecipitation followed by high-throughput DNA sequencing (ChIP-seq) for ICN1 in thymic gd T cells from neonates of C57BL/6 mice. Sequence reads for ICN1 and Input were aligned with the mouse reference genome (mm10) by bowtie program (v1.0.0), and peak detection and ident...
ORGANISM(S): Mus musculus 
2014-11-14 | E-GEOD-56756 | biostudies-arrayexpress
TranscriptomicsGene expression data from undifferentiated mouse embryonal carcinoma cell strains (MOE430A and MOE430B)
Gene expression profiles of undifferentiated mouse embryonal carcinoma cell strains (P19, P19CL6, and 4 P19CL6 sublines) were obtained, using Affymetrix GeneChip Mouse Genome 430A and 430B. Heart diseases such as cardiac infarction damage cardiomyocytes and consequently lead to significant loss of t...
ORGANISM(S): Mus musculus 
2011-01-26 | E-GEOD-26875 | biostudies-arrayexpress
TranscriptomicsIdentification of Myt1 as a subunit of the neural cell type-specific LSD1 complex
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. Recently, dynamic epigenomic regulation, including chromatin remodeling and histone modifications by tra...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-49685 | biostudies-arrayexpress
TranscriptomicsmRNA profile of dG9a-depleted early embryo in Drosophila melanogaster
Immunocytochemical studies revealed that dG9a moves into nucleus after cycle 8 and appears to regulate gene expression by di-methylating H3K9 from cycle 8 to cycle 11. To determine which genes are regulated by dG9a during cycles 8-11, we examined mRNA levels by performing RNA-sequence analysis using...
ORGANISM(S): Drosophila melanogaster 
2015-08-01 | E-GEOD-56665 | biostudies-arrayexpress
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