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TranscriptomicsMicrocolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation.
A hallmark of the biofilm architecture is the presence of microcolonies. However, little is known about the underlying mechanisms governing microcolony formation. In the human pathogen Pseudomonas aeruginosa, microcolony formation is dependent on the two-component regulator MifR, with mifR mutant bi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-30 | E-GEOD-35286 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
MetabolomicsGlycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway configurations ...
2022-01-11 | MTBLS3887 | MetaboLights
MetabolomicsMetabolite profiling of Arabidopsis mutants of enzymes of lower glycolysis
We have previously shown that in Arabidopsis the three enzymes of lower glycolysis phosphoglycerate mutase (PGAM), enolase and pyruvate kinase form a complex which play an important role in co-sub-cellar localization the mitochondria to the chloroplast. Given that their metabolites of these mutants,...
2022-10-10 | MTBLS4066 | MetaboLights
UnknownTribute to Kenneth Sauer (1931-2022): a mentor, a role-model, and an inspiration to all in the field of photosynthesis.
Not available
S-EPMC11615026 | biostudies-literature
UnknownPredicting input signals of transcription factors in Escherichia coli.
Not available
S-EPMC12494820 | biostudies-literature
ProteomicsExtensive regulation of enzyme activity by phosphorylation in Escherichia coli
This project contains intact protein MS and PRM data for several central metabolic enzymes in E.coli. The enzymes are both wild-type and mutant for several
ORGANISM(S): Escherichia coli 
2021-08-20 | PXD027243 | Pride
E coli Top down proteomics Intact protein 
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
UnknownA Combined Experimental and Theoretical Study of ESR Hyperfine Coupling Constants for N,N,N',N'-Tetrasubstituted p-Phenylenediamine Radical Cations.
Not available
S-EPMC9967363 | biostudies-literature
TranscriptomicsEffect of floT and floA mutations on the global transcriptome of Bacillus subtilis NCIB3610
To compare the altered transcript levels in the floT, floA single and floTfloA double mutants of Bacillus subtilis, cells were grown in MSgg medium until the late exponential phase and their transcriptome was compared to the wild type, NCIB3610 strain. Bacillus subtilis NCIB3610 wild type and its fl...
ORGANISM(S): Bacillus subtilis 
2015-12-21 | E-GEOD-47918 | biostudies-arrayexpress
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