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TranscriptomicsMicrocolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation.
A hallmark of the biofilm architecture is the presence of microcolonies. However, little is known about the underlying mechanisms governing microcolony formation. In the human pathogen Pseudomonas aeruginosa, microcolony formation is dependent on the two-component regulator MifR, with mifR mutant bi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-30 | E-GEOD-35286 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
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