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TranscriptomicsHierarchical clustering of PDAC cell lines
Hierarchical clustering of pancreatic cancer cell lines based on differentially regulated genes between mesenchymal and epithelial PDAC cells derived from primary tumours and metastases from KrasG12D-driven mouse models of pancreatic cancer.
ORGANISM(S): Mus musculus 
2022-11-19 | E-MTAB-8173 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression changes of pancreatic tissue from Ptf1aCre;KrasG12D and Ptf1aCre;KrasG12D;SnailKI/+ mice
Comparison of gene expression changes of pancreatic tissue from Ptf1aCre;KrasG12D and Ptf1aCre;KrasG12D;SnailKI/+ mice at the age of 1 month and 3 months.
ORGANISM(S): Mus musculus 
2022-11-19 | E-MTAB-8174 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of pancreatic mouse tumors upon treatment
KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) is highly immunosuppressive and resistant to targeted therapies, immune checkpoint blockade and engineered T cells. In this study, we performed a systematic high throughput combinatorial drug screen and identified a synergistic interaction between ...
ORGANISM(S): Mus musculus 
2021-11-13 | E-MTAB-9954 | biostudies-arrayexpress
TranscriptomicsRNA-seq of pancreatic mouse tumor cell lines
KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) is highly immunosuppressive and resistant to targeted therapies, immune checkpoint blockade and engineered T cells. In this study, we performed a systematic high throughput combinatorial drug screen and identified a synergistic interaction between ...
ORGANISM(S): Mus musculus 
2021-11-29 | E-MTAB-11187 | biostudies-arrayexpress
TranscriptomicsMurine PDAC cell lines
Expression profiles of 28 murine pancreatic cancer cell lines isolated from a KrasG12D-based mouse model of pancreatic cancer mRNA of 28 low passaged murine pancreatic cancer cell lines was extracted and hybridized to Affymetrix microarrays
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-40609 | biostudies-arrayexpress
ProteomicsMass spectrometry-based draft of the mouse proteome
Quantitative draft map of the proteomes of 41 healthy tissues of the animal model Mus musculus and a panel of 66 murine pancreatic ductal adenocarcinoma cell lines and. Our in-depth analysis provides evidence for proteins encoded by >16,000 genes (~76% of the total annotated protein-coding genes), w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-07-09 | MSV000089856 | MassIVE
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