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TranscriptomicsSalvelinus Microarray experiment: selected line vs control line
Domestication has been practiced for centuries yet directed towards relatively few terrestrial crops and animals. While phenotypic and quantitative genetic changes associated with domestication have been amply documented, little is known about the molecular changes underlying the phenotypic evolutio...
ORGANISM(S): Salvelinus fontinalis 
2010-06-24 | E-GEOD-20490 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 675 commonly used human cancer cell lines
Tumor-derived cell lines have served as vital models to advance our understanding of oncogene function and therapeutic response1. Although substantial effort has been directed to defining the genomic constitution of cancer cell line panels24, the transcriptome which represents the active program of...
ORGANISM(S): Homo sapiens 
2014-11-25 | E-MTAB-2706 | biostudies-arrayexpress
GenomicsGenentech Data Access Committee
Data Access Committee EGAC00001000055
EGAC00001000055 | EGA
ProteomicsRepurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
The majority of current therapeutics targeting plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. Typical mammalian proteins, however, consist of multiple domains executing discrete but coordinated activities, and saturating inhibition of one functional domain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-25 | MSV000089542 | MassIVE
GenomicsGenentech RCC DAC
Data Access Committee EGAC00001000247
EGAC00001000247 | EGA
GenomicsGenentech Colon Cancer Screen
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary human colon tumours by applying next-generation sequencing to characterize their exomes, transcriptomes and copy-number alte...
EGAS00001000288 | EGA
GenomicsColon_Illumina_2.5M_Controls - samples
Colon matched tumour samples
EGAD00010000274 | EGA
GenomicsColon_Illumina_2.5M_Cases - samples
Colon tumour samples
EGAD00010000272 | EGA
Genomicsena-DATASET-Genentech-10-08-2012-19:54:35:559-18 - samples
Exome capture sequencing of colon tumor/normal pairs
EGAD00001000216 | EGA
Genomicsena-DATASET-Genentech-10-08-2012-19:45:02:785-17 - samples
RNA sequencing of colon tumor/normal sample pairs
EGAD00001000215 | EGA
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