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TranscriptomicsTranscription profiling of mouse primary macrophages treated with the chemotherapeutic agent, 5,6-dimethylxanthenone-4-acetic acid,
Vascular disrupting agents (VDA) represent a novel approach to the treatment of cancer, resulting in collapse of tumor vasculature and tumor death. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) is a VDA currently in advanced Phase II clinical trials, yet its precise mechanism of action is unknown de...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7194 | biostudies-arrayexpress
TranscriptomicsExpression profile of etoposide-resistant MCF7 (MCF7VP) cells
The second leading cause of cancer death for women in the U.S. is breast cancer. Moreover, a significant number of patients with breast tumors acquire resistance to drugs during therapy. To develop targeted therapeutic strategies to combat drug resistance it is essential to understand the basic mol...
ORGANISM(S): Homo sapiens 
2011-04-08 | E-GEOD-28413 | biostudies-arrayexpress
TranscriptomicsExpression profile of etoposide-resistant MCF7 (MCF7VP) cells with targeted RUNX2 knockdown
The second leading cause of cancer death for women in the U.S. is breast cancer, moreover, a significant number of patients with breast tumors acquire resistance to drugs during therapy. To develop targeted therapeutic strategies to combat drug resistance it is essential to understand the basic mole...
ORGANISM(S): Homo sapiens 
2011-04-08 | E-GEOD-28414 | biostudies-arrayexpress
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