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ProteomicsQuantitative Single-Cell Proteomics as a Tool to Characterize Cellular Hierarchies
Large-scale single-cell analyses are of fundamental importance in order to capture biological heterogeneity within complex cell systems, but have largely been limited to RNA-based technologies. Here we present a comprehensive benchmarked experimental and computational workflow, which establishes glo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-10-21 | MSV000090570 | MassIVE
ProteomicsHigh-throughput and high-sensitivity biomarker monitoring in body fluid by fast LC SureQuant™ IS targeted quantitation
Targeted proteomics methods have been greatly improved and refined over the last decade and are becoming increasingly the method of choice in protein and peptide quantitative assays. Despite the tremendous progress in targeted proteomic assays, they still suffer from inadequate sensitivity for lower...
ORGANISM(S): Homo Sapiens 
PXD032305 | panorama
ProteomicsMatrix metalloproteinase landscape in the imiquimod-induced skin inflammation mouse model
Inflammation and autoimmunity are known as central processes in many skin diseases, including psoriasis. It is therefore important to develop pre-clinical models that describe disease-related aspects to enable testing of pharmaceutical drug candidates and formulations to essentially develop safe and...
ORGANISM(S): Mus Musculus 
2025-10-31 | PXD046049 | panorama
ProteomicsLongitudinal evaluation of biomarkers in wound fluids of venous leg ulcers treated with a protease-modulating wound dressing
Venous leg ulcers (VLU) represent a clinical challenge and impair the patient’s quality of life. Venous insufficiency is underlying the protracted healing. We report the protein expression pattern for biomarkers in VLU wound fluids and compare these with acute split-thickness wound fluids. Fifty-se...
ORGANISM(S): Homo Sapiens 
PXD025748 | panorama
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