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MetabolomicsUrinary microbiota and metabolome in pediatric vesicoureteral reflux and scarring
Not available
ORGANISM(S): Homo sapiens 
ST001649 | MetabolomicsWorkbench
TranscriptomicsConjunctival miRNA expression data in scarring and inflammatory trachoma
Ocular infection with Chlamydia trachomatis (trachoma) is the leading cause of blindness that results from infection. Chronic inflammation is believed to drive the scarring process and the progressive blinding disease, however the mechanisms by which this occurs are not completely understood. We hyp...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-37717 | biostudies-arrayexpress
TranscriptomicsLineage recording in human cerebral organoids (whole organoids)
Induced pluripotent stem cell (iPSC) derived organoid systems provide models to study human organ development. Single-cell transcriptome sequencing enables highly-resolved descriptions of cell state heterogeneity within these systems and computational methods can reconstruct developmental trajectori...
ORGANISM(S): Homo sapiens 
2021-11-03 | E-MTAB-10974 | biostudies-arrayexpress
TranscriptomicsLineage recording in human cerebral organoids (microdissected)
Induced pluripotent stem cell (iPSC) derived organoid systems provide models to study human organ development. Single-cell transcriptome sequencing enables highly-resolved descriptions of cell state heterogeneity within these systems and computational methods can reconstruct developmental trajectori...
ORGANISM(S): Homo sapiens 
2021-11-03 | E-MTAB-10973 | biostudies-arrayexpress
TranscriptomicsLineage recording in human cerebral organoids (Visium)
Induced pluripotent stem cell (iPSC) derived organoid systems provide models to study human organ development. Single-cell transcriptome sequencing enables highly-resolved descriptions of cell state heterogeneity within these systems and computational methods can reconstruct developmental trajectori...
ORGANISM(S): Homo sapiens 
2021-11-03 | E-MTAB-10972 | biostudies-arrayexpress
TranscriptomicsLineage recording in human cerebral organoids (iTracer-perturb)
Induced pluripotent stem cell (iPSC) derived organoid systems provide models to study human organ development. Single-cell transcriptome sequencing enables highly-resolved descriptions of cell state heterogeneity within these systems and computational methods can reconstruct developmental trajectori...
ORGANISM(S): Homo sapiens 
2021-11-03 | E-MTAB-10971 | biostudies-arrayexpress
TranscriptomicsIdentification and Targeted Inhibition of a Fibroblast Lineage Responsible for Scarring and Cancer Stroma
Dermal fibroblasts represent a heterogeneous population of cells with diverse features that remain largely undefined due to a lack of functional subclasses. Here we reveal the presence of multiple lineages of dermal fibroblasts within the dorsal back. Genetic lineage tracing and transplantation assa...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-65402 | biostudies-arrayexpress
TranscriptomicsThe conjunctival transcriptome in scarring trachoma for Tanzanians
Trachoma is a poorly understood immuno-fibrogenic disease process, initiated by Chlamydia trachomatis (Ct). Differences in conjunctival gene expression profiles between Tanzanians with trachomatous conjunctival scarring (with (TSI) and without (TS) inflammation) and controls (C) were investigated to...
ORGANISM(S): Homo sapiens 
2011-07-31 | E-GEOD-24383 | biostudies-arrayexpress
GenomicsJUN promotes hypertrophic skin scarring via CD36
JUN promotes hypertrophic skin scarring via CD36
PRJNA739661 | ENA
ProteomicsTANGO1 inhibitors limit tissue scarring
Scarring is a normal outcome of the wound healing program, but excessive secretion of ECM proteins such as collagen can lead to fibrosis and compromise tissue function. Despite the widespread occurrence of fibrosis, effective therapies are lacking. A promising approach would be to limit the amount o...
ORGANISM(S): Homo sapiens (Human) 
2024-04-28 | PXD041678 | Pride
Tissue scarring Ecm hypersecretion Tango1 
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