Sort   by:  
 Page size 
UnknownA Bacterial Platform for Studying Ubiquitination Cascades Anchored by SCF-Type E3 Ubiquitin Ligases.
Not available
S-EPMC11505812 | biostudies-literature
ProteomicsLayers of regulation on cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae
In the budding yeast Saccharomyces cerevisiae, transcription factors (TFs) regulate the periodic expression of many genes during the cell cycle, including gene products required for progression through cell-cycle events. Experimental evidence coupled with quantitative models suggest that a network o...
ORGANISM(S): Saccharomyces Cerevisiae 
PXD010937 | panorama
TranscriptomicsExpression data from PARK2 overexpression in U251 cells
PARK2 (PARKIN) is an E3 ubiquitin ligase whose dysfunction has been associated with the progression of Parkinsonism and human malignancies, and its role in cancer remains to be explored. In this study, we investigated its role in glioma. We used microarrays to detail the global programme of gene exp...
ORGANISM(S): Homo sapiens 
2014-10-03 | E-GEOD-61973 | biostudies-arrayexpress
TranscriptomicsThe E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
Analysis of gene expression altered upon knockdown of Siah2 in prosate cancer cells. The objective is to elucidate which signaling pathways or transcription factors are regulated by the E3 ubiquitin ligase Siah2 in human prostate cancer cells. CWR22Rv1 cells were in fected with pLKO.1 control or Sia...
ORGANISM(S): Homo sapiens 
2013-03-19 | E-GEOD-38851 | biostudies-arrayexpress
TranscriptomicsBRCT phosphoprotein recognition, but not E3 ligase activity, is essential for BRCA1 tumor suppression
It has been recognized that BRCA1, in the form of the BRCA1/BARD1 heterodimer, acting as an ubiquitin E3 ligase offered a possible mechanism to explain its pleiotrophic nature of BRCA1 activity. Our observation that mice lacking BRCA1 enzymatic activity are viable apart from male sterility was unex...
ORGANISM(S): Mus musculus 
2011-08-25 | E-GEOD-31673 | biostudies-arrayexpress
UnknownSKP1-like protein, CrSKP1-e, interacts with pollen-specific F-box proteins and assembles into SCF-type E3 complex in 'Wuzishatangju' (Citrus reticulata Blanco) pollen.
Not available
S-EPMC7761267 | biostudies-literature
TranscriptomicsExpression Profile Of A Caenorhabditis Elegans Model Of Adult Onset Neuronal Ceroid Lipofuscinosis Reveals Down Regulation Of Ubiquitin E3 Ligase Components.
Transcriptional profiling of two C. elegans mutants of dnj-14, the worm homolog of cysteine string protein (CSP), compared to two control strains N2 (Bristol) and CZ1200. CSP is a neuroprotective protein and the C. elegans mutants, tm3223 and ok237, are used to model the neurodegenerative disease, a...
ORGANISM(S): Caenorhabditis elegans 
2015-12-04 | E-MTAB-3147 | biostudies-arrayexpress
TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant upl3-4 Arabidopsis thaliana plants.
Activation of plant immunity is associated with dramatic transcriptome reprogramming to prioritise immune responses over normal cellular functions. Changes in gene expression are coordinated by the immune hormone salicylic acid (SA). Here we investigated the involvement of the HECT-type ligase Ubiqu...
ORGANISM(S): Arabidopsis thaliana 
2018-11-09 | E-MTAB-7374 | biostudies-arrayexpress
UnknownHistone acetyltransferase CBP promotes function of SCF FBXL19 ubiquitin E3 ligase by acetylation and stabilization of its F-box protein subunit.
Not available
S-EPMC6191137 | biostudies-literature
UnknownUbiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Not available
S-EPMC7904520 | biostudies-literature
Sort   by:  
 Page size