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Metabolomicstargeted metabolomics detemination of SCFA
Podophyllotoxin (PPT) exhibits limited clinical utility due to its nephrotoxicity, and its underlying mechanisms remain poorly understood. This study employs the toxicological evidence chain (TEC) framework and integrated multi-omics analyses to investigate the potential involvement of the microbiot...
2026-06-28 | MTBLS14873 | MetaboLights
MetabolomicsExtracellular Vesicles from probiotics mediated Walnut green husk polysaccharide alleviates ochratoxin-A-induced cognitive impairment via SCFA and 5-HT mediated microbiota-gut-brain axis

BACKGROUND: Ochratoxin A (OTA) have made it a serious hazard to food safety worldwide that poses a serious health risk to humans. Our previous research showed that Walnut green husk polysaccharides (WGP) can effectively alleviate intestinal inflammation and intestinal microbiota ...

2024-10-10 | MTBLS10673 | MetaboLights
MetabolomicsSCFA in Hypertension
Not available
ORGANISM(S): Rattus norvegicus 
ST000191 | MetabolomicsWorkbench
MetabolomicsHirschprung Enterocolitis SCFA
Not available
ORGANISM(S): Homo sapiens 
ST000189 | MetabolomicsWorkbench
MetabolomicsSodium Butyrate mediates Histone Crotonylation and Alleviated Neonatal Rats Hypoxic-Ischemic Brain Injury Through Gut-Brain Axis (targeted SCFA brain metabolomics)

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-10-12 | MTBLS4933 | MetaboLights
MetabolomicsMCFA and SCFA in fecal pellets from mice on different diets
Not available
ORGANISM(S): Mus musculus 
ST000760 | MetabolomicsWorkbench
TranscriptomicsComparison of the effects of five dietary fibers on mucosal transcriptional profiles, and luminal microbiota composition and SCFA concentrations in murine colon
Consumption of diets rich in fibers has been associated with several beneficial effects on gastrointestinal health. However, detailed studies on the molecular effects of fibers in colon are limited. In this study we investigated and compared the influence of five different fibers on the mucosal tran...
ORGANISM(S): Mus musculus 
2015-05-26 | E-GEOD-59494 | biostudies-arrayexpress
MetabolomicsDetermination and comparison of SCFAs in serum and colon content samples: Alzheimer's disease rat as a case study (SCFA serum and colon content determination)

SCFAs are the main microbial fermentation products from dietary fibers in colon and play a key role in keeping healthy in the whole-body. However, differences of SCFAs concentration in the serum and colon samples collected from rats had attracted few attentions. Here, we optimized the extract and...

2020-11-24 | MTBLS2088 | MetaboLights
MetabolomicsSCFA profile in infants dying of SIDS
Not available
ORGANISM(S): Homo sapiens 
ST000715 | MetabolomicsWorkbench
MetabolomicsInfluence of excercise and antiobitic on fecal SCFA
Not available
ORGANISM(S): Rattus norvegicus 
ST000710 | MetabolomicsWorkbench
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