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TranscriptomicsHematopoietic cells-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury
Chronic liver injury triggers complications such as liver fibrosis and hepatocellular carcinoma (HCC), which are associated with alterations in distinct signaling pathways. Of particular interest is the interaction between mechanisms controlled by IKKγ/NEMO, the regulatory IKK subunit, and Jnk activ...
ORGANISM(S): Mus musculus 
2015-06-22 | E-GEOD-59601 | biostudies-arrayexpress
ProteomicsA microbiome-dependent gut brain pathway regulates motivation for exercise
Exercise exerts a wide range of beneficial effects for healthy physiology. However, the mechanisms regulating an individual's motivation to engage in physical activity remain incompletely understood. An important factor stimulating the engagement in both competitive and recreational exercise is the ...
ORGANISM(S): Mouse 
2023-03-15 | MSV000091494 | MassIVE
TranscriptomicsInfection exposure promotes ETV6-RUNX1 precursor B cell leukemia revealing secondary genomic alterations in histone modification genes
We used microarrays to investigate gene expression changes in ETV6/RUNX1 proB and preB cells Bone marrow proB and preB cells of four ETV6/RUNX1 mice compared with bone marrow proB and preB cells of three WT mice and three Pax5+/- mice.
ORGANISM(S): Mus musculus 
2015-07-03 | E-GEOD-70492 | biostudies-arrayexpress
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