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ProteomicsPeripheral positioning of lysosomes supports melanoma aggressiveness
Peripheral positioning of lysosomes supports melanoma aggressiveness
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD042007 | Pride
Exosomes 
ProteomicsSingle-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
The chromatin at origins of replication is thought to influence DNA replication initiation in eukaryotic genomes. However, it remains unclear how the chromatin composition controls the firing of early-efficient (EE) or late-inefficient (LI) origins. Here, we used site-specific recombination and sing...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-02-16 | PXD032930 | Pride
Locus-specific chromatin isolation  site-specific recombination  affinity purification  dna replication origin  replication timing  replication efficiency  origin chromatin structure  dash complex  ask1 protein  microtubule cytoskeleton 
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