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TranscriptomicsPolysome profiling of glp-4 mutant animals
To determine the translational status of mRNAs in glp-4 mutant animals, we analyzed total and polysomal RNA levels by tiling arrays A total of 8 samples was analyzed (quadruplicates of glp-4_total and glp-4_polysomal, respectively)
ORGANISM(S): Caenorhabditis elegans 
2015-01-08 | E-GEOD-62860 | biostudies-arrayexpress
TranscriptomicsIdentification of GLD-1 target mRNAs
To determine which mRNAs are bound by GLD-1 we performed GLD-1 and MYC (as a negative control) immunoprecipitation experiments on wildtype animals. A total of 6 samples was analyzed (triplicates of GLD-1 IPs and MYC IPs respectively)
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-33081 | biostudies-arrayexpress
TranscriptomicsmRNA expression analysis in wild-type, gld-1 and cgh-1 mutant animals
To determine mRNA expression levels in wild-type, gld-1 (q485) mutant and cgh-1(tn691) mutant animals, RNA was purified from dissected gonads of young adult worms, using the PicoPur Kit. A total of 9 samples was analyzed (triplicates of wild-type, gld-1 mutant and cgh-1 mutant animals respectively)
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-33082 | biostudies-arrayexpress
TranscriptomicsmRNA expression analysis in mock and cgh-1(RNAi) animals
To determine mRNA expression levels in mock and cgh-1(RNAi) animals, RNA was purified from young adult worms, using Trizol. A total of 6 samples was analyzed (triplicates of mock and cgh-1(RNAi) animals respectively)
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-36713 | biostudies-arrayexpress
TranscriptomicsGLD-1 mRNA regulation
This SuperSeries is composed of the following subset Series: GSE33081: Identification of GLD-1 target mRNAs GSE33082: mRNA expression analysis in wild-type, gld-1 and cgh-1 mutant animals GSE33083: Polysome profiling of wild-type and gld-1 mutant animals GSE36713: mRNA expression analysis in mock an...
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-33084 | biostudies-arrayexpress
TranscriptomicsPolysome profiling of wild-type and gld-1 mutant animals
To determine the translational status of mRNAs in wild-type and gld-1 mutant animals, we analyzed total and polysomal RNA levels in both strains by tiling arrays A total of 16 samples was analyzed (quadruplicates of wild-type_total, wild-type_polysomal, gld-1_total, gld-1_polysomal RNA respectively)
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-33083 | biostudies-arrayexpress
TranscriptomicsRNAseq in Alzheimer's Disease patients
Human brain samples from healthy and advanced Alzheimer's diseased patients were subjected to RNA-seq analysis to monitor RNA level changes during AD progression. Human brain samples were obtained from the Mount Sinai Brain Bank; RNA was Trizol extracted, ribominus selected and submitted for high-th...
ORGANISM(S): Homo sapiens 
2016-02-17 | E-GEOD-53697 | biostudies-arrayexpress
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