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ProteomicsBurger_et_al_ilicicolin_metabolomics
In this study, the ilicicolin biosynthetic gene cluster (BGC) in Trichoderma reesei was genetically activated, and a series of gene cluster enzyme deletions were performed. Mycelia were harvested and subjected to polar extraction. The resulting polar extracts were analyzed using an untargeted lipido...
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) 
MSV000095813 | MassIVE
ProteomicsDiscovery of a novel antifungal compound, ilicicolin K, through genetic activation of the ilicicolin biosynthetic pathway in Trichoderma reesei
In the quest to discover novel antifungal agents and new antifungal production processes, we investigated the biosynthetic gene cluster (BGC) for ilicicolin H in the fungus Trichoderma reesei. While the BGC is silent under standard cultivation conditions, we achieved to activate it by over-expressi...
ORGANISM(S): Trichoderma reesei 
2025-03-13 | PXD055742 | Pride
Multi-omics Fungi Natural products 
ProteomicsSpatially resolved activity-based lipolytic proteomic profiles of the murine small intestine
Despite the crucial function of the small intestine for nutrient uptake our understanding of the molecular events underlying the digestive function is very rudimentary. For example, it has only recently become evident that not all absorbed triacylglycerol (TAG) is immediately secreted in the form of...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-11 | PXD019593 | Pride
Small intestine Lipases Activitz based proteomics Mouse 
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