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TranscriptomicsThe AHL- and BDSF-dependent quorum sensing systems control specific and overlapping sets of genes in Burkholderia cenocepacia H111
Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones (AHLs) and the diffusible signal factor cis-2-dodecenoic acid (BDSF). Previous studies have shown that AHLs and BDSF control similar phenotypic...
ORGANISM(S): Burkholderia cenocepacia H111 
2012-11-01 | E-GEOD-41244 | biostudies-arrayexpress
TranscriptomicsThe IclR-family regulator BapR controls biofilms formation in B. cenocepacia H111
In Burkholderia cenocepacia H111, the large surface protein BapA plays a crucial role in the formation of highly structured communities, known as biofilms. We have recently demonstrated that Quorum sensing (QS) is necessary for the maximal expression of bapA. In this study we identify a protein from...
ORGANISM(S): Burkholderia cenocepacia H111 
2014-03-26 | E-GEOD-52769 | biostudies-arrayexpress
TranscriptomicsThe effect of sleep restriction on transcriptome rhythmicity in mice
Timed sleep restriction designed to mimic human shift work was performed over a 2 week period in mice. On the final day, tissues were collected at 6 hour intervals to exmaine the effects of sleep restriction on circadian gene expression. 3 mice were used at each time point, for both controls and sle...
ORGANISM(S): Mus musculus 
2012-04-20 | E-GEOD-33381 | biostudies-arrayexpress
TranscriptomicsMapping the quorum sensing regulon of Burkholderia cenocepacia H111
Comparative transcriptional profiling of the Burkholderia cenocepacia H111 wild type, the cepR mutant H111-R and the complemented cepR mutant H111-R (pBAH27).
ORGANISM(S): Burkholderia cenocepacia 
2011-05-01 | E-MTAB-509 | biostudies-arrayexpress
Transcriptomicss54 -dependent response to nitrogen limitation and virulence in Burkholderia cenocepacia H111
Members of the genus Burkholderia are versatile bacteria capable of colonizing highly diverse environmental niches. In this study, we investigated the global response of the opportunistic pathogen Burkholderia cenocepacia H111 to nitrogen limitation at the transcript and protein expression level. In...
ORGANISM(S): Burkholderia cenocepacia H111 
2015-04-29 | E-GEOD-66328 | biostudies-arrayexpress
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