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ProteomicsEngineering an Extremely Hybrid PKS for Adipic Acid Production
Polyketide synthases (PKSs) are modular enzymes with exceptional potential as biocatalysts for producing non-native compounds. Here, we report the first PKS-based pathway for adipic acid (AA), an industrial monomer for nylon production, by engineering one of the most extensively hybridized PKS syste...
ORGANISM(S): Pseudomonas putida KT2440 
2026-09-07 | PXD069956 | Pride
Hybrid pks Polyketide synthase Adipic acid P. putida Jbei E. coli 
ModelsMetabolic model of Sulfolobus solfataricus
Metabolic model of Sulfolobus solfataricus
2017-04-24 | 231 | FAIRDOMHub
UnknownMortality and Causes of Death in Patients with Sporadic Inclusion Body Myositis: Survey Study Based on the Clinical Experience of Specialists in Australia, Europe and the USA.
Not available
S-EPMC5271419 | biostudies-literature
TranscriptomicsMyomgraft_Model_TASIP_2010_09
Human uterine fibroids are benign tumors derived from the smooth muscle layers of the uterus. Fibroid disease impacts up to 50% of premenopausal women in their daily life, and accounts for up to 50% of hysterectomies in the United States. Despite the health burden they impose, the development of the...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-MTAB-1882 | biostudies-arrayexpress
GenomicsThe ets transcription factor ELF5 suppresses the estrogen sensitive phenotype and contributes to antiestrogen resistance in luminal breast cancer. [human ChIP-Seq]
The ets transcription factor ELF5 specifies the differentiation of mammary progenitor cells to establish the milk-secreting lineage. ER- and poor prognosis basal breast cancers arise from this progenitor cell and these cancers express high levels of Elf5. Knockdown of ELF5 expression in basal breast...
ORGANISM(S): Homo sapiens 
2012-12-27 | E-GEOD-31216 | biostudies-arrayexpress
UnknownCerebral malaria is associated with differential cytoadherence to brain endothelial cells.
Not available
S-SCDT-87729_2_1551692040_jats | biostudies-other
Genomicsena-DATASET-DKFZ-Epigenomics-19-11-2015-09:37:32:058-207 - samples
RNA-seq of peripheral blood samples from CLL patients.
EGAD00001001675 | EGA
Genomicsena-DATASET-DKFZ-Epigenomics-19-11-2015-09:41:10:900-208 - samples
Tagmentation-based whole-genome bisulfite sequencing of isolated cell types from healthy controls.
EGAD00001001676 | EGA
Genomics450K_DKFZ_CLL_NB
CLL and normal B cell samples using 450K
EGAD00010000871 | EGA
GenomicsAnalysis of DNA methylation in normal B cells and chronic lymphocytic leukemia
Charting differences between tumors and normal tissue is a mainstay of cancer research. However, clonal tumor expansion from complex normal tissue architectures potentially obscures cancer-specific events, including divergent epigenetic patterns. Using whole-genome bisulfite sequencing of normal B c...
EGAS00001000534 | EGA
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