Sort   by:  
 Page size 
MetabolomicsMass spectrometry based metabolomics for in vitro systems pharmacology: Pitfalls, challenges, and computational solutions

INTRODUCTION: Mass spectrometry based metabolomics has become a promising complement and alternative to transcriptomics and proteomics in many fields including in vitro systems pharmacology. Despite several merits, metabolomics based on liquid chromatography mass spectrometry (LC...

2017-08-23 | MTBLS401 | MetaboLights
TranscriptomicsNew target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion
IGR39 cells, seeded at a density of 6x104 cells/well in 12-well culture plates, were transfected with 5 nM of miR-211 mimic or negative control (NCM) as described in the main text. Samples for total RNA extraction were collected 48h after transfection. RNA quality was assessed using RNA 6000 NanoChi...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-MEXP-3749 | biostudies-arrayexpress
TranscriptomicsUPC2 Is universally essential for Azole antifungal resistance in Candida albicans
In Candida albicans, the transcription factor Upc2 is central to the regulation of ergosterol biosynthesis. UPC2-activating mutations contribute to azole resistance, whereas disruption increases azole susceptibility. In the present study, we investigated the relationship of UPC2 to fluconazole susce...
ORGANISM(S): Candida albicans 
2014-05-24 | E-GEOD-57929 | biostudies-arrayexpress
Sort   by:  
 Page size