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UnknownPolygenic prediction of treatment efficacy with causal transfer learning.
Not available
S-EPMC12633083 | biostudies-literature
ProteomicsMtr complex and MtrI quantification from Methanosarcina mazei
This dataset contains LC-MS/MS data from multiple experiments investigating the N⁵-methyltetrahydromethanopterin:CoM-S-methyltransferase (Mtr) complex of Methanosarcina mazei, with quantitative analysis performed using MaxQuant. Experiment 1: Strep-Tactin-based purification of the native Mtr comple...
ORGANISM(S): Methanosarcina mazei Go1 
2026-01-19 | PXD064689 | Pride
Archaea Methanogen Methanosarcina Mtr complex Maxquant Small protein 
UnknownA quantile integral linear model to quantify genetic effects on phenotypic variability.
Not available
S-EPMC9522331 | biostudies-literature
Proteomics,MultiomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080878 | MassIVE
UnknownWidespread long-range cis-regulatory elements in the maize genome.
Not available
S-EPMC6904520 | biostudies-literature
UnknownPIGEON: a statistical framework for estimating gene-environment interaction for polygenic traits.
Not available
S-EPMC12496094 | biostudies-literature
ProteomicsMacrophage development and activation involve coordinated intron retention in key inflammatory regulators
Monocytes and macrophages are essential components of the innate immune system. Herein, we report that intron retention (IR) plays an important role in the development and function of these cells. Using mRNA sequencing, bioinformatics analyses and RT-qPCR validation, we identified differential IR an...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD017391 | Pride
Human Monocyte Macrophage 
TranscriptomicsInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Monocyte chemoattractant protein 1 (MCP-1/CCL2) is critically involved in directing the migration of blood monocytes to sites of inflammation. Consequently, excessive MCP-1 secretion has been linked to many (auto)inflammatory diseases, whereas a lack of expression severely impairs immune responsiven...
ORGANISM(S): Mus musculus 
2013-04-09 | E-GEOD-43075 | biostudies-arrayexpress
UnknownRepeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
Not available
S-EPMC11100705 | biostudies-literature
UnknownMass Spectrometric Metabolic Fingerprinting of 2-Deoxy-D-Glucose (2-DG)-Induced Inhibition of Glycolysis and Comparative Analysis of Methionine Restriction versus Glucose Restriction under Perfusion Culture in the Murine L929 Model System.
Not available
S-EPMC9408990 | biostudies-literature
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