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TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
TranscriptomicsPPARγ controls alveolar macrophage identity
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-09-28 | E-GEOD-60249 | biostudies-arrayexpress
UnknownCorrelative VIS-fluorescence and soft X-ray cryo-microscopy/tomography of adherent cells.
Not available
S-EPMC3343273 | biostudies-literature
TranscriptomicsPPARγ controls alveolar macrophage identity [part1]
Tissue-resident macrophages comprise heterogeneous populations with unique functions and distinct gene expression signatures. While it has been established that they mostly originate from embryonic progenitors, the signals inducing a characteristic tissue-specific differentiation program remain unkn...
ORGANISM(S): Mus musculus 
2014-09-28 | E-GEOD-60247 | biostudies-arrayexpress
TranscriptomicsPPARγ controls alveolar macrophage identity [part2]
Tissue-resident macrophages comprise heterogeneous populations with unique functions and distinct gene expression signatures. While it has been established that they mostly originate from embryonic progenitors, the signals inducing a characteristic tissue-specific differentiation program remain unkn...
ORGANISM(S): Mus musculus 
2014-09-28 | E-GEOD-60248 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-sequencing of epithelial cells, endothelial cells and macrophages from mouse submandibular salivary glands
The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in chronic dry mouth. This leads to detrimental effects on their health and quality of life, for which there is no regenerative therapy. Macrophages are the predominant immune cell in t...
ORGANISM(S): Mus musculus 
2023-10-01 | E-MTAB-13374 | biostudies-arrayexpress
UnknownDynorphin-Based "Release on Demand" Gene Therapy for Drug-Resistant Temporal Lobe Epilepsy
Not available
S-SCDT-EMM-2018-09963 | biostudies-other
UnknownMachine Learning Based Prediction of COVID-19 Mortality Suggests Repositioning of Anticancer Drug for Treating Severe Cases.
Not available
S-EPMC8677630 | biostudies-literature
TranscriptomicsCAR-adapted PIK3CD base editing enhances T cell anti-tumor potency
Insufficient functional T cell persistence impedes therapeutic success of chimeric antigen receptor (“CAR”) therapies. Here, we performed a CAR-adapted base editing screen of PIK3CD, a key regulator of T cell function, metabolism, and fate. We identified point mutations that beneficially modulate CA...
ORGANISM(S): Homo sapiens 
2025-11-06 | E-MTAB-15749 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of pancreatic ductal adenocarcinoma xenograft models
We generated novel patient derived xenograft (PDX) and cell line -derived xenograft models for pancreatic ductal adenocarcinoma (PDAC) which reflect different molecular subtypes. Pancreatic ductal adenocarcinoma is currently the tumor with the fourth highest mortality rate. Recently, subtypes of PDA...
ORGANISM(S): Homo sapiens 
2016-01-12 | E-MTAB-4029 | biostudies-arrayexpress
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