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MetabolomicsImproving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry
Untargeted metabolomics aims at obtaining quantitative information on the highest possible number of low-molecular biomolecules present in a biological sample. Rather small changes in mass spectrometric spectrum acquisition parameters may have a significant influence on the detectabilities of metabo...
2016-06-09 | MTBLS233 | MetaboLights
ProteomicsHuman cerebrospinal fluid analysis by data-independent analysis The Cerebrospinal fluid samples were denaturated and reduced.
Cerebrospinal fluid samples of patients with Parkinson’s disease and healthy controls were used in this study. After tryptic digestion, all samples were spiked with indexed retention time (iRT) peptides and were measured using a DIA mass spectrometry approach.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022234 | Pride
Human Dia Cerebrospinal fluid Parkinsons disease 
TranscriptomicsPHH Chlorpromazine
Drug induced liver injury (DILI) is still a major reason for drug attrition during clinical trials and market-withdrawal of already approved drugs. DILI is difficult to predict in animal models, hence more suitable screening methods are needed to predict adverse effects in human. Here, transcriptom...
ORGANISM(S): Homo sapiens 
2013-08-05 | E-MTAB-1747 | biostudies-arrayexpress
TranscriptomicsAmplification and overexpression of vinculin are associated with increased tumor cell proliferation and progression in advanced prostate cancer
We analyzed the 10q22 amplification in advanced prostate cancer and subjected the genes located in the common amplified region to an RNAi screen. We found vinculin as the most promising candidate gene and analyzed its protein expression on more than 400 prostate cancers by using the tissue micrarray...
ORGANISM(S): Homo sapiens 
2011-02-08 | E-GEOD-24216 | biostudies-arrayexpress
UnknownEomesodermin-expressing CD4 Th cells and association with multiple sclerosis progression and brain atrophy.
Not available
S-EPMC12673330 | biostudies-literature
UnknownChoroid plexus enlargement associates with serum neurofilament and predicts relapse-free progression in multiple sclerosis.
Not available
S-EPMC12923943 | biostudies-literature
UnknownPharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study.
Not available
S-EPMC8843022 | biostudies-literature
Genomicsena-DATASET-RTL-10-04-2014-14:57:02:227-16 - samples
Fernandez-Cuesta et al, 2014, Nature Communication, Whole exome sequencing data set
EGAD00001000820 | EGA
Genomicsena-DATASET-RTL-03-04-2014-12:58:19:275-109 - samples
Fernandez-Cuesta et al., 2014, Nature Communication, Whole genome sequencing was performed using a read length of 2x100 bp for all samples. On average, 110 Gb of sequence were produced per sample, aiming a mean coverage of 30x for both tumour and matched normal.
EGAD00001000813 | EGA
Genomicsena-DATASET-RTL-26-03-2014-08:44:34:042-926 - samples
Fernandez-Cuesta et al, 2014, Nature Communication, RNA Sequencing data set
EGAD00001000795 | EGA
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