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TranscriptomicsThe MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset (RNAi)
The MOF-containing NSL complex binds to many but not all promoters of active genes and potentially contributes to their proper gene expression. It is currently unknown what determines whether an active gene is bound or not. Here, we provide evidence that the NSL complex primarily targets active prom...
ORGANISM(S): Drosophila melanogaster 
2011-10-28 | E-GEOD-30990 | biostudies-arrayexpress
MetabolomicsChlorophyll biosynthesis under the control of arginine metabolism.

In natural environments, photosynthetic organisms adjust their metabolism to cope with the fluctuating availability of combined nitrogen sources, a growth-limiting factor. For acclimation, the dynamic degradation/synthesis of tetrapyrrolic pigments, as well as of the amino acid arginine, is ...

2024-03-12 | MTBLS8336 | MetaboLights
UnknownPolymorphism of CD14 Gene Is Associated with Adverse Outcome among Patients Suffering from Cardiovascular Disease.
Not available
S-EPMC8282382 | biostudies-literature
TranscriptomicsThe MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset
This SuperSeries is composed of the following subset Series: GSE30989: MOF-containing NSL complex specifically binds promoters of most, but stimulates only a specific subset of, housekeeping genes (ChIP-chip dataset) GSE30990: MOF-containing NSL complex specifically binds promoters of most, but stim...
ORGANISM(S): Drosophila melanogaster 
2011-10-28 | E-GEOD-30991 | biostudies-arrayexpress
MetabolomicsSpecific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To characterize the biosyntheti...
2021-10-06 | MTBLS1819 | MetaboLights
TranscriptomicsPolycomb repressive complex 2-dependent and M-bM-^@M-^Sindependent functions of Jarid2 in transcriptional regulation in Drosophila [Affymetrix]
Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2 recruitment in mouse embryonic stem cells. Although Jarid2 is conserved in Drosophila, it has not previously been implicated in Polycomb (Pc) regulation...
ORGANISM(S): Drosophila melanogaster 
2012-02-23 | E-GEOD-36038 | biostudies-arrayexpress
UnknownRandomized, double-blind, placebo-controlled, multicenter phase II study of the efficacy and safety of apricoxib in combination with either docetaxel or pemetrexed in patients with biomarker-selected non-small-cell lung cancer.
Not available
S-EPMC4890680 | biostudies-literature
UnknownRandomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer.
Not available
S-EPMC5320944 | biostudies-literature
UnknownMetal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2.
Not available
S-EPMC3512400 | biostudies-literature
UnknownRapid and recent world-wide diversification of bluegrasses (Poa, Poaceae) and related genera.
Not available
S-EPMC3609727 | biostudies-literature
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