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TranscriptomicsReal-time Monitoring of Cisplatin Toxicity on Cancer Cells
Treatment of MCF7 breast cancer cells by cisplatin leads to a very specific metabolic response and an onset of cell death about 10-11 h after beginning of treatment. For more detailed understanding of the molecular processes underlying the specific metabolic response, mRNA was isolated from MCF7 cel...
ORGANISM(S): Homo sapiens 
2011-04-04 | E-GEOD-28274 | biostudies-arrayexpress
TranscriptomicsDistinct and Overlapping Gene Regulatory Networks in BMP- and HDAC-Controlled Cell Fate Determination in the Embryonic Forebrain
Both bone morphogenetic proteins (BMPs) and histone deacetylases (HDACs) have previously been established to play a role in the development of the three major cell types of the central nervous system: neurons, astrocytes, and oligodendrocytes. We have previously established a connection between thes...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-31792 | biostudies-arrayexpress
TranscriptomicsGene expression of Lymphoblastoid Cell Lines (LCLs) from Depressed Patients after in-vitro treatment with fluoxetine
We used whole gene gene expression profiling to identify potential gene expression biomarkers associated for the treatment individualization of depressive disorders. Gene expression was measured after 21 days of in-vitro treatment with therapeutical concentrations of fluoxetine in n=10 LCLs derived ...
ORGANISM(S): Homo sapiens 
2016-06-15 | E-GEOD-83386 | biostudies-arrayexpress
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