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TranscriptomicsGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
The HMG-box factor Tcf1 is required during T-cell development in the thymus and mediates the nuclear response to Wnt signals. Tcf1-/- mice have previously been characterized and show developmental blocks at the CD4-CD8- double negative (DN) to CD4+CD8+ double positive transition. Due to the blocks i...
ORGANISM(S): Mus musculus 
2014-02-14 | E-GEOD-54976 | biostudies-arrayexpress
TranscriptomicsDiagnosis-relapse in ALL
Almost a quarter of pediatric patients with Acute Lymphoblastic Leukemia (ALL) suffer from relapses. The biological mechanisms underlying therapy response and development of relapses have remained unclear. In an attempt to better understand this phenomenon, we have analyzed 41 matched diagnosis rel...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-18497 | biostudies-arrayexpress
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