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TranscriptomicsExpression data from normal and transplanted islets in non-pregnant and pregnant condition
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59143 | biostudies-arrayexpress
TranscriptomicsExpression data from islets of Pdx1-creLate, control and pregnant mice
ABSTRACT: The human growth hormone (hGH) minigene is frequently used in transgenic mouse lines to ensure proper transgene expression. Here, we show that hGH is expressed in islets isolated from the commonly used Pdx1-CreLate mouse model. Locally secreted hGH activates prolactin receptors on M-NM-2 c...
ORGANISM(S): Mus musculus 
2014-02-14 | E-GEOD-50851 | biostudies-arrayexpress
TranscriptomicsExpression data from islets of non-pregnant and pregnant PRLR+/+ and PRLR-/- mice
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59141 | biostudies-arrayexpress
TranscriptomicsmRNA analysis in different mouse tissues
The functioning of a specific tissue depends on the expression pattern of the different genes. We used microarrays to compare gene expression across different murine tissues, to get a better understanding in the expression pattern and functioning of the different tissues. With this analysis, we were...
ORGANISM(S): Mus musculus 
2010-11-18 | E-GEOD-24207 | biostudies-arrayexpress
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