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ProteomicsLu_C16orf72_APMS_293_P36_Elite_VS37
This dataset consists of 6 raw MS files and associated peak lists and results files, acquired on Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by YiQing Lu. BioID and Mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was pe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-11 | MSV000093630 | MassIVE
ProteomicsLu_C16orf72_APMS_U2OS_P36_Elite_VS38
This dataset consists of 6 raw MS files and associated peak lists and results files, acquired on Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by YiQing Lu. BioID and Mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was pe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-11 | MSV000093632 | MassIVE
TranscriptomicsThe stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression
Transcriptional profiling of control and MKK7-deficient primary mouse pneumocytes after oncogenic KRasG12 induction Two-condition experiment, MKK7 proficient vs. MKK7 deficient pneumocytes. 3 Biological replicates: 3 control, 3 knock out, independently grown and harvested. 3 technical replicates p...
ORGANISM(S): Mus musculus 
2011-01-21 | E-GEOD-26763 | biostudies-arrayexpress
ProteomicsHesketh_BioID_HOPS-mTORC1_2019
This submission is associated with a paper by Hesketh et al. that identifies the GATOR-Rag GTPase pathway as a negative regulator of mTORC1 activation by lysosome-derived amino acids.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-30 | MSV000084159 | MassIVE
GenomicsChIP-seq of CTCF, RAD21, and TOP2B binding sites in three human tissue samples with hepatocellular carcinoma
The roles of topoisomerases in somatic mutagenesis in cancer are poorly understood and their DNA-binding landscape remains largely unmapped. Here we generated genome-wide DNA-binding maps of TOP2B, CTCF, and RAD21 in human hepatocellular carcinoma samples.
ORGANISM(S): Homo sapiens 
2024-02-01 | E-MTAB-13301 | biostudies-arrayexpress
TranscriptomicsRNA-seq of the primary patient-derived GBM cell line G797 following siRNA-mediated knockdown and pcDNA3.1-Neomycin-mediated overexpression of the lncRNA HOXA10-AS
We used a machine-learning framework to systematically discover prognostic long non-coding RNAs (lncRNAs) in 9,446 patient tumors of 30 types. We identified 166 prognostic lncRNAs whose transcript abundance correlated with patient risk and improved the performance of common clinical variables and mo...
ORGANISM(S): Homo sapiens 
2021-10-02 | E-MTAB-10944 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human mammary epithelial cell line MCF10A with RMRP/CCDC107/ARHGEF39-targeted CRISPR edits vs. scramble controls
The purpose of these experiments was to validate the role of a frequently mutated regulatory element bound by TOP2B using a functional genomics approach. Specifically, CRISPR/Cas9 was employed to selectively target the promoter of RMRP and non-coding regions of CCDC107 and ARHGEF39.
ORGANISM(S): Homo sapiens 
2025-01-01 | E-MTAB-14611 | biostudies-arrayexpress
ProteomicsPoirson_TPD_timsTOFPro2_VS13_14
This dataset consists of 18 raw DDA MS files and associated peak lists and results files, acquired on timsTOF Pro2 mass spectrometer operated in Data Dependent Acquisition-PASEF (Parallel accumulation-serial fragmentation) mode. It also consists of 18 raw DIA MS files acquired in Data Independent-PA...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-26 | MSV000093202 | MassIVE
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