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TranscriptomicsSAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining
Aberrant end joining of DNA double strand breaks leads to chromosomal rearrangements and to insertion of nuclear or mitochondrial DNA into breakpoints, which is commonly observed in cancer cells and constitutes a major threat to genome integrity. However, the mechanisms that are causative for these ...
ORGANISM(S): Homo sapiens 
2021-01-20 | E-MTAB-8382 | biostudies-arrayexpress
TranscriptomicsInvestigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia
Activation induced deaminase (AID) has two distinct and well defined roles, both relying on its deoxycytidine (dC) deaminating function: one as a DNA mutator and another in DNA demethylation. In chronic lymphocytic leukemia (CLL), AID was previously shown to be an independent negative prognostic fac...
ORGANISM(S): Homo sapiens 
2018-11-29 | E-MTAB-7431 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Mesenchymal Stem Cells (MSC) vs reference RNA of non-multipotent human fibroblasts HS68
Mesenchymal stem cells (MSC) resemble a multipotent adult stem cell population capable of differentiation into a number of different mesodermal cell types including adipodytes, osteoblasts, chondroblasts. Although still in debate there is some evidence, that these cells can also differentiate into c...
ORGANISM(S): Homo sapiens 
2005-08-23 | E-EMBL-4 | biostudies-arrayexpress
UnknownThe Role of Electroencephalography in Predicting Post-Stroke Seizures and an Updated Prognostic Model (SeLECT-EEG).
Not available
S-EPMC12542305 | biostudies-literature
UnknownChimeric Antigen Receptor (CAR) T Cell Therapy in Acute Myeloid Leukemia (AML).
Not available
S-EPMC6406805 | biostudies-literature
UnknownA randomised, double-blind trial comparing budesonide formulations and dosages for short-term treatment of eosinophilic oesophagitis.
Not available
S-EPMC4789829 | biostudies-literature
UnknownTumor-Specific Reactive Oxygen Species Accelerators Improve Chimeric Antigen Receptor T Cell Therapy in B Cell Malignancies.
Not available
S-EPMC6566309 | biostudies-literature
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownAssociation of Mortality and Risk of Epilepsy With Type of Acute Symptomatic Seizure After Ischemic Stroke and an Updated Prognostic Model.
Not available
S-EPMC10087089 | biostudies-literature
Unknown12-hr shifts in nursing: Do they remove unproductive time and information loss or do they reduce education and discussion opportunities for nurses? A cross-sectional study in 12 European countries.
Not available
S-EPMC6916398 | biostudies-literature
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