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TranscriptomicsLarge-scale analysis of the mouse transcriptome
We used microarrays to compare gene expression across different murine tissues. Keywords: Other Different tissues were dissected from 10-12 week old C57Bl6 mice for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2007-12-20 | E-GEOD-9954 | biostudies-arrayexpress
TranscriptomicsExpression data from normal and transplanted islets in non-pregnant and pregnant condition
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59143 | biostudies-arrayexpress
TranscriptomicsTranscription in adult mouse tissues
We used Affymetrix Gene Arrays (1.0 ST) to compare gene expression across different murine tissues. Arrays were used to find disallowed genes in tissues. Different tissues were dissected from 10-12 week old C57Bl6 mice for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-24940 | biostudies-arrayexpress
TranscriptomicsGene expression profile of myeloma cells treated with IGF-1
Objective of this study was to find changes in gene expression of mouse multiple myeloma cells upon treatment with IGF-1 Murine multiple myeloma cells were incubated in serum free medium for 12 hours in the absence (3 replicates) or presence (3 replicates) of 100 ng/ml IGF-1
ORGANISM(S): Mus musculus 
2010-03-09 | E-GEOD-17140 | biostudies-arrayexpress
TranscriptomicsExpression data from islets of non-pregnant and pregnant PRLR+/+ and PRLR-/- mice
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59141 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of colonic mucosa biopsies in patients with inflammatory bowel disease
Microarrays were used to analyze the gene expression in endoscopic-derived intestinal mucosal biopsies from patients with inflammatory bowel disease (IBD) and controls Mucosal biopsies were obtained at endoscopy from the colon of 97 ulcerative colitis (UC), 8 Crohn's disease (CD) patients and 11 co...
ORGANISM(S): Homo sapiens 
2015-05-27 | E-GEOD-59071 | biostudies-arrayexpress
TranscriptomicsCOX-2 network as predictive molecular marker for clinical pregnancy in IVF
CONTEXT Nowadays, the molecular mechanisms involved in endometrial receptivity and implantation are still not clear. OBJECTIVE The gene expression of human endometrium of patients undergoing an IVF treatment with GnRH antagonists/rec-FSH was studied. CONCLUSIONS COX-2 has been extensively studied ...
ORGANISM(S): Homo sapiens 
2010-09-06 | E-GEOD-18140 | biostudies-arrayexpress
TranscriptomicsLow dose hCG pregnant vs non-pregnant
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-09-07 | E-GEOD-21225 | biostudies-arrayexpress
TranscriptomicsMucosal expression profiling in patients with inflammatory bowel disease before and after first infliximab treatment
We used microarrays to identify mucosal gene signatures predictive of response to infliximab (IFX) in patients with inflammatory bowel disease (IBD) and to gain more insight into the pathogenesis of IBD. Keywords: drug response and treatment effect Mucosal biopsies were obtained at endoscopy in act...
ORGANISM(S): Homo sapiens 
2009-11-02 | E-GEOD-16879 | biostudies-arrayexpress
TranscriptomicsMucosal gene signatures to predict response to infliximab in patients with ulcerative colitis
Infliximab, an anti-TNF-alpha monoclonal antibody, is an effective treatment for ulcerative colitis (UC) with over 60% of patients responding to treatment and up to 30% reaching remission. The mechanism of resistance to anti-TNF-alpha is unknown. This study used colonic mucosal gene expression to pr...
ORGANISM(S): Homo sapiens 
2010-01-06 | E-GEOD-14580 | biostudies-arrayexpress
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