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Transcriptomics
(2)
Organisms
Mus musculus
(2)
Repository
biostudies-arrayexpress
(2)
Instrument Platform
Illumina NovaSeq 6000
(2)
Publication Date
2021
(2)
Study type
High-throughput sequencing
(1)
RNA-seq of coding RNA
(1)
Release Date
2021
(2)
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RNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
Mice with colonic tumors (chemically induced by AOM/DSS) were treated with Nutlin or control vehicle solution to analyze p53 target gene expression in vivo.
ORGANISM(S):
Mus musculus
2021-04-20
|
E-MTAB-10041
|
biostudies-arrayexpress
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Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
p53LOH in murine CRC organoids de-represses HSF1 activity and triggers mutp53-driven invasion.
ORGANISM(S):
Mus musculus
2021-05-17
|
E-MTAB-10416
|
biostudies-arrayexpress
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