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There is a current need to monitor human exposure to a large number of pesticides and other chemicals of emerging concern (CECs). This requires screening analysis with high confidence for these compounds and their metabolites in complex matrices, which is hampered by the fact that no reference stand...
2022-01-17 | MTBLS2402 | MetaboLights
Transcriptional profiling of human glioma cells to elucidate the role of chronophin (CIN/PDXP) for glioma pathogenesis three-condition experiment: control cells vs. knockdown and knockdown vs. rescue
ORGANISM(S): Homo sapiens 
Genome-wide comparative gene expression analysis of callus tissue of osteoporotic mice (Col1a1-Krm2 and Lrp5-/-) and wild-type were performed to identify candidate genes that might be responsible for the impaired fracture healing observed in Col1a1-Krm2 and Lrp5-/- mice. To investigate bone healing ...
ORGANISM(S): Mus musculus 
Nitrate nutrtition was withdrawn from Arabiodpsis plants to study early responses upon nitrate depletion. Plants were grown under full nutrition (3mM nitrate) for three weeks and then transferred to nutrient solution without nitrate for 15 minutes and 3 hours.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-05-21 | PXD015390 | Pride
Quorum sensing (QS) is a mechanism of intercellular communication that enables microbes to alter gene expression and adapt to the environment. While QS has been extensively studied in bacteria, little is known about cell-cell communication in archaea. We could show that for Haloferax volcanii, the t...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) Archaea 
2025-06-17 | PXD059278 | Pride
Cell shape plays a crucial role in microbial survival. While Haloferax volcanii, a model haloarchaeon, forms rods and disks, depending on environmental conditions, little is known about mechanisms underpinning archaeal cell-shape determination. We identified mutants that exclusively form rods and ca...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) Archaea 
2024-02-17 | PXD040781 | Pride
To define the molecular regulators required for differential pattern of H3K79 methylation by Dot1, we performed a GPS screen and discovered that the components of the cell cycle-regulated SBF complex were required for normal levels of H3K79 di- but not trimethylation. Genome-wide mapping revealed t...
ORGANISM(S): Saccharomyces cerevisiae 
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