Schuster Anne A

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Stavrum2013 - Tryptophan Metabolism in Liver

Stavrum2013 - Tryptophan Metabolism in Liver This model is described in the article: Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data. Stavrum AK, Heiland I, Schuster S, Puntervoll P, Ziegler M. J. Biol. Chem. 2013 Nov; 288(48): ...

2024-09-02 | BIOMD0000000602 | BioModels

Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

ChIP-seq is used to map transcription factor occupancy and generate epigenetic profiles genome-wide. The requirement of nano-scale ChIP DNA for generation of sequencing libraries has impeded ChIP-seq on in vivo tissues of low cell numbers. We describe a robust, simple and scalable methodology for Ch...

ORGANISM(S): Mus musculus

2015-02-01 | E-GEOD-55850 | biostudies-arrayexpress

Pre-leukemic Cebpa mutant myeloid progenitors

In this study, we use pre-malignant cells from different Cebpa mutant acute myeloid leukemia (AML) models. We have used conditional KO models (CreLoxP) and isolated hematopoietic cells shortly after induction of recombination, in order to look at pre-leukemic cells, which have acquired the first hit...

ORGANISM(S): Mus musculus

2013-07-08 | E-GEOD-47813 | biostudies-arrayexpress

C/EBPa is required for self-renewal, lineage priming and maintenance of epigenetic configurations in hematopoietic stem cells

Transcription factors are key regulators of hematopoieticstem cells (HSCs) and act through their ability to bind DNA andimpact on gene transcription. Their functions are interpreted inthe complex landscape of chromatin but current knowledge on howthis is achieved is very limited. C/EBPa is an import...

ORGANISM(S): Mus musculus

2013-12-01 | E-GEOD-43007 | biostudies-arrayexpress

Cash water expenditures are associated with household water insecurity, food insecurity, and perceived stress in study sites across 20 low- and middle-income countries.

Not available

S-EPMC9988664 | biostudies-literature

Simvastatin in Critically Ill Patients with Covid-19.

Not available

S-EPMC10755839 | biostudies-literature

Swiss-wide multicentre evaluation and prediction of core outcomes in arthroscopic rotator cuff repair: protocol for the ARCR_Pred cohort study.

Not available

S-EPMC8070866 | biostudies-literature

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.