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TranscriptomicsTranscription profiling of mouse 3T3-F442A adipocytes treated with or without growth hormone (GH) to identify a mechanism for regulation of activating transcription factor 3 by GH
Expression profiling of 3T3-F442A adipocytes treated with growth hormone (GH, 500 nM) or vehicle (DMEM + 1% BSA) control for 30 min., 4 hr., or 48 hr in three independent experiments. Chronic GH treatment induces metabolic changes consistent with insulin resistance in 3T3-F442A adipocytes.
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-2120 | biostudies-arrayexpress
MetabolomicsTranscriptomics and Metabolomics Reveal Alterations in Xenobiotic Metabolism and Appearance of Steroidal Alkaloid Metabolites in Mouse Livers after Tomato Consumption

SCOPE: Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. It is hypothesized that tomato phytochemicals are transported to the liver and other tissues where they alter gene expression in ways that lead to favorable he...

2023-06-13 | MTBLS6715 | MetaboLights
UnknownPost-imaging pulmonary nodule mathematical prediction models: are they clinically relevant?
Not available
S-EPMC6717521 | biostudies-literature
TranscriptomicsGENOMIC ANALYSIS OF FIBROLAMELLAR HEPATOCELLULAR CARCINOMA REVEALS A UNIQUE MOLECULAR PROFILE
Fibrolamellar hepatocellular carcinoma (FLC) is a rare primary hepatic cancer usually developed in non-cirrhotic livers of children and young adults with unknown etiology. Treatment is limited to surgical intervention. To date, molecular pathogenesis of FLC has been poorly characterized. A cohort of...
ORGANISM(S): Homo sapiens 
2015-02-12 | E-GEOD-59443 | biostudies-arrayexpress
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
GenomicGWAS of Preterm Birth

Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...

phs000332 | dbGaP
UnknownRABGAP1 is a sensor that facilitates the sorting and processing of amyloid precursor protein
Not available
S-SCDT-10_1038-S44318-025-00530-0 | biostudies-other
UnknownStromal Fibroblast Growth Factor 2 Reduces the Efficacy of Bromodomain Inhibitors in Uveal Melanoma
Not available
S-SCDT-87277_3_1544692587_jats | biostudies-other
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