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TranscriptomicsExpression data from mammary macrophages isolated from MMTV-iFGFR1 transgenic mice
The goal of this experiment was to profile macrophages from mammary glands isolated from transgenic mice that express inducible FGFR1 in mammary epithelial cells (MMTV-iFGFR1 transgenic mice). The mice were treated with with dimerizer to activates iFGFR1 for 48 hours and 4 weeks to induce mammary hy...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-36477 | biostudies-arrayexpress
ProteomicsUnique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
The activity of Src-family kinases (SFKs), which phosphorylate immunoreceptor tyrosine-based activation motifs (ITAMs), is a critical factor regulating myeloid-cell activation. In a previous paper (Freedman et al., 2015) we showed that the SFK LynA is uniquely susceptible to rapid ubiquitin-mediated...
ORGANISM(S): Mus Musculus 
PXD014621 | panorama
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