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Breast cancer is the most common malignancy that develops in women, responsible for the highest cancer-associated death rates. Triple negative breast cancers (TNBC) represent an important subtype that have an aggressive clinical phenotype, are associated with a higher likelihood of metastasis and ar...
ORGANISM(S): Homo sapiens 
Fibrotic and nonfibrotic bronchial tissues were collected from lungs of pentandione exposed rats by laser capture microdissection. Analogous tissue was collected from air-exposed controls. Miroarray analysis revealed a number of DEGs Male Wistar Han rats were exposed to either air or 200 ppm 2,3-pen...
ORGANISM(S): Rattus norvegicus 
Data Access Committee EGAC00001002686
This dataset contains one vcf file with variants from whole exome sequencing of 24 paediatric AML samples at diagnosis.
Analysis of rare germline variants in childhood AML in a large panel of cancer predisposition genes (n=216) compiled from literature review, and including genes involved in familial hematological malignancies (HM) and bone marrow failure (BMF) syndromes. The prevalence of extremely rare variants in ...
Although mutations in p53 are infrequent in human melanoma, its function is abnormal. In this study, whole genome bead arrays were used to examine the expression of p53 target genes in extracts from 6 melanoma cell lines, compared to extracts derived from diploid human melanocytes and fibroblasts, t...
ORGANISM(S): Homo sapiens 
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