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UnknownCoordinated repression of totipotency-associated gene loci by histone methyltransferase EHMT2 through binding to LINE-1 regulatory elements.
Not available
S-EPMC11702699 | biostudies-literature
UnknownLoss of 5-hydroxymethylcytosine is a frequent event in peripheral T-cell lymphomas.
Not available
S-EPMC5830377 | biostudies-literature
UnknownA bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus.
Not available
S-EPMC8628258 | biostudies-literature
UnknownRHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.
Not available
S-EPMC5811310 | biostudies-literature
UnknownAIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes.
Not available
S-EPMC5943248 | biostudies-literature
UnknownNfkbie-deficiency leads to increased susceptibility to develop B-cell lymphoproliferative disorders in aged mice.
Not available
S-EPMC7070037 | biostudies-literature
TranscriptomicsB-cell tumor development in Tet2-deficient mice
The TET2 gene encodes an α-ketoglutarate-dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in B- and T-cell malignancies. TET2 somatic mutations are also id...
ORGANISM(S): Mus musculus 
2019-12-12 | E-MTAB-8501 | biostudies-arrayexpress
UnknownB-cell tumor development in Tet2-deficient mice.
Not available
S-EPMC5873234 | biostudies-literature
UnknownDNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Not available
S-EPMC4869893 | biostudies-literature
TranscriptomicsIGR_U985_CLL_EGR2_GE_STUDY_OB
Chronic lymphocytic leukemia (CLL), the most frequent adult leukemia in western countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL m...
ORGANISM(S): Mus musculus 
2014-06-18 | E-MTAB-1764 | biostudies-arrayexpress
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