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TranscriptomicsscRNA-seq of first and second trimester human reproductive tract
scRNA-seq of first and second trimester human reproductive tract (including female and male internal and external genitalia)
ORGANISM(S): Homo sapiens 
2025-08-07 | E-MTAB-15475 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of stromal vascular cells from 48 week (aged) mouse subcutaneous adipose tissue compared to control 10 week (young) mouse SVF
Adipose tissue mass and adiposity change throughout the lifespan. During aging, while visceral adipose tissue (VAT) tends to increase, peripheral subcutaneous adipose tissue (SAT) decreases significantly. Unlike VAT, which is linked to metabolic diseases, SAT has beneficial effects. However, the mol...
ORGANISM(S): Mus musculus 
2021-03-25 | E-MTAB-10221 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal duodenal enteroids grown in EGF and/or NRG1
The purpose of this study was to interrogate the role of EGF-family ligands, in particular Epidermal Growth Factor (EGF) and Neuregulin 1 (NRG1), as human intestinal stem cell niche factors. An established duodenal enteroid line derived from a 20.2 week post conception biological specimen was expose...
ORGANISM(S): Homo sapiens 
2020-12-10 | E-MTAB-9720 | biostudies-arrayexpress
ProteomicsProteomic and single-cell transcriptomic dissection of human plasmacytoid dendritic cell response to influenza virus
Plasmacytoid dendritic cells [pDCs] represent a rare innate immune subset uniquely endowed with the capacity to produce substantial amounts of type-I interferons [IFN-I]. This function of pDCs is critical for effective antiviral defenses and has been implicated in autoimmunity. While IFN-I and selec...
ORGANISM(S): Human Plasmacytoid Dendritic Cell 
2021-11-12 | MSV000088375 | MassIVE
TranscriptomicsscRNA-seq of intestinal epithelial organoids derived from human fetal duodenum
Here, we used single-cell RNA-sequencing (scRNA-seq) to profile intestinal epithelial only organoids (also known as enteroids) from human fetal duodenum after one passage of in vitro growth. Organoids were grown in the standard 25% LWRN media with either 100 ng/ml of EGF or 1 ng/ml of EREG added.
ORGANISM(S): Homo sapiens 
2022-07-17 | E-MTAB-11912 | biostudies-arrayexpress
TranscriptomicsDISC-seq: deciphering cell stress heterogeneity through joint mapping of cellular damage and transcriptomic landscapes in scRNA-seq
Cell heterogeneity is a fundamental feature of biological systems, driving diverse responses to stimuli and stressors, including developmental cues, diseases, and drug treatments. While single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to characterize this diversity by profiling ...
ORGANISM(S): Homo sapiens 
2026-04-19 | E-MTAB-16932 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomic profiling of 16 synovial sarcoma tumors
This study investigates the cellular heterogeneity of Synovial Sarcoma (SyS), an aggressive cancer defined by the SS18-SSX fusion oncogene and exhibiting diverse clinical behavior. We used single-cell RNA sequencing (scRNA-seq) on tumor samples from 16 patients to deconstruct this diversity at high ...
ORGANISM(S): Homo sapiens 
2025-10-16 | E-MTAB-15748 | biostudies-arrayexpress
TranscriptomicsscRNA-seq and scTCR-seq of tetramer-positive T cells from IL27 treated tumor bearing mice
To characterize the consequences of systemic IL-27R agonism via IL-27 overexpression or IL-27 blockade (αIL-27) on anti-tumor CTL, we performed scRNA-seq of M86 neoantigen-specific CD8+ T cells from MC38 tumors and dLN.
ORGANISM(S): Mus musculus 
2024-12-05 | E-MTAB-14601 | biostudies-arrayexpress
TranscriptomicsscRNA-seq data for Distinct Stem Cell Identities Converge into Shared Erythroid Stress in ERCC6L2 Disease and Shwachman-Diamond Syndrome
This study includes single-cell RNA sequencing of human samples across ERCC6L2 disease (ED), Shwachman-Diamond syndrome (SDS), acute myeloid leukemia (AML), and healthy controls. ED, SDS, and AML samples were processed for single-cell capture, followed by library preparation and sequencing. Sequenci...
ORGANISM(S): Homo sapiens 
2026-06-03 | E-MTAB-16984 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal intestine tissue
Here, we performed single cell RNA sequencing (scRNA-seq) of human fetal duodenal tissue samples from 8 individual biological specimens across 7-21 weeks of gestation. The data set is composed of over 37,000 cells (between 3,000-9,000 cells per time point) from diverse intestinal lineages. Lineages ...
ORGANISM(S): Homo sapiens 
2020-12-12 | E-MTAB-9489 | biostudies-arrayexpress
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