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UnknownSecond-Hit, Postzygotic PMVK and MVD Mutations in Linear Porokeratosis.
Not available
S-EPMC6506890 | biostudies-literature
UnknownSecond hit impels oncogenesis of retinoblastoma in patient-induced pluripotent stem cell-derived retinal organoids: direct evidence for Knudson's theory.
Not available
S-EPMC9802398 | biostudies-literature
UnknownMaternal Deprivation Enhances Contextual Fear Memory via Epigenetically Programming Second-Hit Stress-Induced Reelin Expression in Adult Rats.
Not available
S-EPMC6209857 | biostudies-literature
ProteomicsGene-environment interaction elicits dystonia-like features and impaired translational regulation in a DYT-TOR1A mouse model
DYT-TOR1A dystonia is a movement disorder characterized by involuntary muscle contractions. Despite being the most common monogenetic form of dystonia, its pathophysiolofy remains unclear. With a reduced penetrance of about 30%, there is a suggestion that extragenetic factors are needed to develeop ...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-05 | PXD047531 | Pride
Second-hit hypothesis Multi-omic Dyt-tor1a 
UnknownSynergistic stress exacerbation in hippocampal neurons: Evidence favoring the dual-hit hypothesis of neurodegeneration.
Not available
S-EPMC4949116 | biostudies-literature
UnknownMutation in BMPR2 Promoter: A 'Second Hit' for Manifestation of Pulmonary Arterial Hypertension?
Not available
S-EPMC4500409 | biostudies-literature
UnknownCOVID-19: A double threat to takotsubo cardiomyopathy and spontaneous coronary artery dissection?
Not available
S-EPMC7680528 | biostudies-literature
GenomicsComparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq
The goal of the ChIP-seq study was to investigate the distribution of the TATA-binding protein (TBP) across the human genome. TBP is the DNA-binding subunit of the basal transcription factor TFIID for RNA polymerase II (pol II) and it also participates in other complexes for the other RNA polymerase...
ORGANISM(S): Homo sapiens 
2010-03-02 | E-GEOD-17937 | biostudies-arrayexpress
UnknownA "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport.
Not available
S-EPMC3099701 | biostudies-literature
UnknownUnderstanding the pathophysiological mechanisms in the pediatric non-alcoholic fatty liver disease: The role of genetics.
Not available
S-EPMC4462683 | biostudies-literature
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