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MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
TranscriptomicsIntegrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
The saprophytic mold Aspergillus fumigatus produces small (2-3 µm) airborne spores (conidia) that can reach the lung alveoli upon inhalation. There, they encounter the surfactant-rich environment of the alveolar epithelium and initiate swelling and germination. Primary alveolar macrophages are essen...
ORGANISM(S): Homo sapiens 
2026-10-02 | E-MTAB-17130 | biostudies-arrayexpress
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