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TranscriptomicsTime course of oxidative stress responses in yeast, caused by Menadione or hydrogen peroxide
Oxidative stress caused by Menadione or Hydrogen peroxide in synchronized Saccharomyces cerevisiae cultures. Alpha factor synchronized cultures (0.2-0.4 OD), treated at the beginning of S phase (25 min after release from G1 arrest) with either 2 mM Menadione (MD) or 0.24 mM Hydrogen peroxide (HP), s...
ORGANISM(S): Saccharomyces cerevisiae 
2005-02-04 | E-GEOD-2239 | biostudies-arrayexpress
TranscriptomicsModule map of stem cell genes guides creation of epithelial cancer stem cells
Self-renewal is a hallmark of stem cells and cancer, but existence of a shared stemness program remains controversial. Here we construct a gene module map to systematically relate transcriptional programs in embryonic stem cells (ESCs), adult tissue stem cells, and human cancers. This map reveals tw...
ORGANISM(S): Homo sapiens 
2008-04-10 | E-GEOD-10423 | biostudies-arrayexpress
TranscriptomicsRevealing Targeted Therapy for Human Cancer by Gene Module Maps
A major goal of cancer research is to match specific therapies to molecular targets in cancer. Genome-scale expression profiling has identified new subtypes of cancer based on consistent patterns of variation in gene expression, leading to improved prognostic predictions. However, how these new gene...
ORGANISM(S): Homo sapiens 
2010-06-29 | E-GEOD-8957 | biostudies-arrayexpress
TranscriptomicsProbing the effect of promoters on noise in gene expression using thousands of designed sequences
Genetically identical cells exhibit large variability (noise) in gene expression, with important consequences for cellular function. Although the amount of noise decreases with and is thus partly determined by the mean expression level, the extent to which different promoter sequences can deviate aw...
ORGANISM(S): synthetic construct 
2014-07-12 | E-GEOD-55346 | biostudies-arrayexpress
UnknownA mixed method approach to understanding the impact of COVID-19 on patients with or at risk for aortic dissection.
Not available
S-EPMC8864810 | biostudies-literature
UnknownEffects of medical therapies on retinopathy progression in type 2 diabetes.
Not available
S-EPMC4026164 | biostudies-literature
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