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TranscriptomicsCGH of common Candida albicans strains
The purpose of this review is to describe the tools used to detect genome changes, to highlight recent advances in our understanding of large scale chromosome changes that arise in C. albicans and to discuss the role of specific stresses in eliciting these genome changes. The types of genomic divers...
ORGANISM(S): Candida albicans 
2010-06-01 | E-GEOD-21643 | biostudies-arrayexpress
TranscriptomicsCGH analysis of Candida albicans strains
Aneuploidy and the evolution of aneuploid karyotypes of Candida albicans strains was identified using aCGH. Whole chromosome and segmental aneuploidies, (specifically on the left arm of chromosome 5 - shown to be due to isochromosome formation) are associated with the appearance of resistance to th...
ORGANISM(S): Candida albicans 
2006-06-30 | E-GEOD-4995 | biostudies-arrayexpress
TranscriptomicsCGH analysis of Candida albicans strains after in vitro evolution in the presence or absence of Fluconazole
Here we provide, for the first time, a longitudinal study of the prevalence, dynamics, and fixation of gross chromosomal rearrangements, including aneuploidy, in the presence and absence of fluconazole during a well-controlled in vitro evolution experiment. While no aneuploidy was detected in any o...
ORGANISM(S): Candida albicans 
2010-06-24 | E-GEOD-16423 | biostudies-arrayexpress
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