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GmNAC81 involved in leaf senecence and drought stress
Gene expression profiling of stress-induced senescence and paracrine senecence in human hepatocytes
We examined the transcriptome induced by GmNAC81 overexpression and leaf senescence and showed that GmNAC81 further modulates leaf senescence by regulating an extensive repertoire of functionally characterized senescence-associated genes (SAGs). GmNAC81 overexpression also uncovered the regulation o...
ORGANISM(S): Glycine max 
2020-10-24 | GSE159910 | GEO
Differentially transcribed miRNAs in stress-induced premature senecence (SIPS)
Detection of senescence-associated miRNAs differentially transcribed during early (D7) and late stages (D21) of human dermal fibroblast (HDF) senescence
ORGANISM(S): Homo sapiens 
2018-06-08 | GSE95354 | GEO
The goal of this experiment was to analyse transcriptomic changes between Biliary epithelial cells or BECs from the liver of mice treated with Acetaminophen (a drug that causes acute liver injury) in combination with AAV8-Tbg-p21 viral vector to induce hepatocyte senecence. The aim was to understand...
ORGANISM(S): Mus musculus 
2023-11-17 | GSE242847 | GEO
Hepatocytes undergo senescence during development and progression of NAFLD. In order to better understand the phenotype of these senescent cells we generated an in vitro model of stress-induced senescence in IHH cells. To further understand the dynamic regulation of paracrine senescence, IHH cells w...
ORGANISM(S): Homo sapiens 
2024-09-01 | GSE210140 | GEO
A transcriptomic time-course study was performed on the senescence process in flag leaves of the spring wheat cultivar Bobwhite grown in the green-house. Leaf samples were harvested at eight time-points from the time of ear emergence until 50% yellowing of the harvested leaf sample.
ORGANISM(S): Triticum aestivum 
The healthspan of mice is enhanced by selectively killing senescent cells using a transgenic suicide gene. Achieving the same using small molecules would have a tremendous impact on quality of life and burden of age-related chronic diseases. As senescent cells resist apoptosis, we used microarrays t...
ORGANISM(S): Homo sapiens 
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